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A Controlled Study of a Group Mindfulness Intervention for Individuals Living With Inflammatory Bowel Disease.

Kate Neilson, Maria Ftanou, Kaveh Monshat, Mike Salzberg, Sally Bell, Michael A Kamm, William Connell, Simon R Knowles, Katherine Sevar, Sam G Mancuso, David Castle

Inflammatory bowel diseases March 2016 DOI: 10.1097/mib.0000000000000629 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Controlled trial (treatment-as-usual control) Peer reviewed
Sample size 60
Population Patients with inflammatory bowel disease
Intervention MI-IBD)
Duration 8-week intervention; follow-up immediately after intervention and 6 months after intervention
Topics Meditation
Key findings A mindfulness-based stress reduction program produced significantly greater improvements than treatment as usual in anxiety, quality of life, and mindfulness immediately after the 8-week intervention, with reductions in depression and gains in quality of life and mindfulness maintained at 6-month follow-up. The authors report medium-to-large effects and conclude the intervention is feasible, acceptable, and effective for patients with inflammatory bowel disease.

Abstract

This study aimed to evaluate the feasibility, acceptability, and effectiveness of a mindfulness-based intervention for patients with inflammatory bowel disease (MI-IBD). Treatment-as-usual control versus mindfulness-based stress reduction intervention. Sixty patients participated in either the MI-IBD (n = 33) or treatment-as-usual group (n = 27) conditions. The MI-IBD consisted of an 8-week mindfulness-based stress reduction training group. Outcome measures were administered at baseline (before intervention), immediately after intervention, and 6 months after intervention. Primary outcomes included measures of quality of life, psychological distress (depression and anxiety), and mindfulness. Data for MI-IBD group participants also included weekly attendance, daily minutes meditated, and satisfaction with the program. There were no baseline differences between intervention and control groups on demographic variables or inflammatory bowel disease severity. Compared with the control group, the MI-IBD group reported significantly greater improvements in anxiety, quality of life, and mindfulness at after intervention, with reduction in depression and improvements in quality of life and mindfulness maintained at 6 months after intervention. Results demonstrate the feasibility, acceptability, and efficacy of a mindfulness intervention for patients with inflammatory bowel disease, with medium-to-large effects on psychological distress, quality of life, and mindfulness.

Comparable studies

Other non-randomized and open-label trials on meditation, most cited first.

Study Year Design Participants
Mindfulness-Based Stress Reduction in Relation to Quality of Life, Mood, Symptoms of Stress, and Immune Parameters in Breast and Prostate Cancer Outpatients Early-stage breast and prostate cancer patients 2003 Pre-post intervention study n = 59
Exploring self‐compassion and empathy in the context of mindfulness‐based stress reduction (MBSR) Community sample 2010 Pre-post intervention study
Mindfulness-Based Stress Reduction Lowers Psychological Distress In Medical Students Second-year medical students 2003 Prospective nonrandomized cohort-controlled study n = 302
Intensive meditation training, immune cell telomerase activity, and psychological mediators. Retreat participants and matched controls 2011 Controlled trial with wait-list control group n = 60
The Effectiveness of Mindfulness Training for Children with ADHD and Mindful Parenting for their Parents Children aged 8-12 with ADHD and their parents 2011 Within-group waitlist controlled trial n = 22

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