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Prenatal Mindfulness Training and Race-Related Vigilance

R. G. Gregory, Natalie N Watson-Singleton, Amanda Desmarattes, Shaquanna Brown, Ghada Bourjeily, Nkenna Odom, Melissa Guillen, Kate M. Guthrie, Margaret H. Bublitz

The Journal of cardiovascular nursing September 23, 2026 DOI: 10.1097/jcn.0000000000001395 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Randomized controlled trial with qualitative interviews Peer reviewed
Sample size 53
Population Pregnant women of color (Hispanic and/or non-white) at risk for developing hypertension in pregnancy; qualitative interviews with 9 Black or Latina women
Intervention Mindfulness training
Measures race-related vigilance, prolonged activation and anticipatory race-related stress scales
Topics Meditation
Key findings Mindfulness training was associated with a significant decrease in race-related vigilance relative to usual care (F = 4.64, P = .04). Qualitative interviews confirmed and extended this, with participants describing race-specific stressors and how mindfulness helped reduce reactions to stressors. The authors conclude that mindfulness may reduce race-related vigilance during pregnancy and that broader efforts are needed to address discriminatory healthcare policies and practices.

Abstract

Background: The experience of discrimination among pregnant women of color is linked to adverse pregnancy outcomes. Mindfulness training, in which participants are taught to observe stressors with acceptance and curiosity, may mitigate psychological consequences of discrimination. However, prior trials of mindfulness have lacked racial and ethnic diversity and may not be culturally congruent among women of color.

Objective: To assess the effects of prenatal mindfulness training on psychological consequences of discrimination as well as barriers and facilitators to mindfulness training, in a sample of pregnant women of color at risk for developing hypertension in pregnancy.

Methods: We included 53 participants enrolled in a clinical trial of mindfulness training who self-identified as women of color (race/ethnicity of Hispanic and/or non-white). Participants completed measures of race-related vigilance and prolonged activation and anticipatory race-related stress scales before and after randomization to mindfulness training or usual care. Qualitative interviews were conducted among 9 Black or Latina women who participated in the mindfulness intervention to identify barriers and facilitators to mindfulness training engagement.

Results: We observed a significant decrease in race-related vigilance after mindfulness training relative to usual care (F = 4.64, P = .04). Qualitative results confirmed and extended these findings with information from participants on their experiences of race-specific stressors as well as how mindfulness served as a tool for reducing reactions to stressors.

Conclusions: Mindfulness may reduce race-related vigilance during pregnancy. In addition to individually delivered interventions, broader efforts are needed to address discriminatory policies and practices within healthcare systems to reduce racial disparities in pregnancy outcomes.

Comparable studies

Other randomized controlled trials on meditation, most cited first.

Study Year Design Participants
Alterations in Brain and Immune Function Produced by Mindfulness Meditation Healthy employees in a work environment 2003 Randomized controlled trial n = 41
Prevention of relapse/recurrence in major depression by mindfulness-based cognitive therapy. Recovered recurrently depressed patients 2000 Randomized controlled trial n = 145
Open hearts build lives: Positive emotions, induced through loving-kindness meditation, build consequential personal resources. Working adults 2008 Randomized controlled trial n = 139
Short-term meditation training improves attention and self-regulation Undergraduate Chinese students 2007 Randomized controlled trial n = 40
Mindfulness-Based Cognitive Therapy for Depression: Replication and Exploration of Differential Relapse Prevention Effects. Recovered recurrently depressed patients 2004 Randomized controlled trial n = 73

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