Hallucinogen-persisting Perception Disorder in a 21-year-old Man.
Muhannad Kurtom, Ashley Henning, Eduardo D. Espiridion
Cureus February 14, 2019 DOI: 10.7759/cureus.4077 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Case study Case report Peer reviewed |
|---|---|
| Sample size | 1 |
| Population | A 21-year-old man with hallucinogen-persisting perception disorder |
| Topics | LSD |
| Keywords | Perception Hallucinogen Hppd Persisting |
| Key findings | The report describes hallucinogen-persisting perception disorder in a 21-year-old man, characterized by flashbacks of visual hallucinations following previous hallucinogenic drug use. The authors state there is no standard treatment and that management combines pharmaceuticals with lifestyle modifications, and they contend the disorder's rarity and severe life impact distinguish it from other substance-induced conditions. |
Abstract
This is a case report of hallucinogen-persisting perception disorder in a 21-year-old man. Hallucinogen-persisting perception disorder, or acute hallucinogen-induced psychosis, is a rare disorder characterized by the presence of flashbacks of visual hallucinations as a result of previous hallucinogenic drug use. There is no standard of treatment, and management involves a combination of pharmaceuticals and lifestyle modifications. The combination of the rarity of the disorder along with the drastic impact this disorder has on a person's life makes this condition unique as compared to other substance-induced conditions.
Comparable studies
Other case reports and case series on LSD, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Lasting Neuropsychiatric Sequelae of (??)Methylenedioxymethamphetamine (???Ecstasy???) in Recreational Users Persons who ingested large doses of MDMA | 1991 | Case study | n = 2 |
| Further Studies in the Therapeutic Value of Lysergic Acid Diethylamide in Mental Illness Patients with mental illness | 1957 | Case series | |
| Coma, Hyperthermia, and Bleeding Associated with Massive LSD Overdose a Report of Eight Cases People who self-administered large amounts of pure LSD powder intranasally | 1975 | Case series | n = 8 |
| Using a MDMA- and LSD-Group Therapy Model in Clinical Practice in Switzerland and Highlighting the Treatment of Trauma-Related Disorders Patients with chronic complex post-traumatic stress disorder (c-PTSD), dissociative,... | 2022 | Case series | |
| Persistent Palinopsia Following Ingestion of Lysergic Acid Diethylamide (LSD) Patients who developed persistent palinopsia after LSD ingestion | 1996 | Case series | n = 3 |
Citations in the library
Cited by 14
- Psychedelics in Psychiatry: Neuroplastic, Immunomodulatory, and Neurotransmitter Mechanisms Pharmacological Reviews December 16, 2020
- Hallucinogenic Persisting Perception Disorder: A Case Series and Review of the Literature Frontiers in Neurology May 6, 2022
- Hallucinogen persisting perception disorder: A literature review and three case reports Journal of Addictive Diseases October 2, 2018
- EMBARK Psychedelic Therapy for Depression March 6, 2024
- Natural language analysis of the structure of altered states of consciousness Journal of Psychedelic Studies May 17, 2025
and 9 more in the library
Cites 4
- Hallucinogen Persisting Perception Disorder: Etiology, Clinical Features, and Therapeutic Perspectives Brain Sciences March 16, 2018
- The “Endless Trip” among the NPS Users: Psychopathology and Psychopharmacology in the Hallucinogen-Persisting Perception Disorder. A Systematic Review Frontiers in Psychiatry November 20, 2017
- Hallucinogen-persisting perception disorder Therapeutic Advances in Psychopharmacology October 1, 2012
- Hallucinogen persisting perception disorder: what do we know after 50 years? Drug and Alcohol Dependence March 1, 2003