A mindful yoga intervention for young women with major depressive disorder: Design and baseline sample characteristics of a randomized controlled trial
Nina K. Vollbehr, Rogier Hoenders, Agna A. Bartels‐Velthuis, Maaike H. Nauta, Stynke Castelein, Maya J. Schroevers, A Dennis Stant, Peter J. de Jong, Brian D. Ostafin
International Journal of Methods in Psychiatric Research February 17, 2020 DOI: 10.1002/mpr.1820 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Randomized controlled trial Peer reviewed |
|---|---|
| Population | Young females aged 18-34 years with major depressive disorder |
| Interventions | Mindful yoga intervention treatment as usual |
| Duration | 9-week intervention; assessments at preintervention, postintervention, 6-month, and 12-month follow-up |
| Measures | Hamilton Depression Rating Scale, Depression-Anxiety-Stress Scales |
| Topics | Depression |
| Citations | 17 |
| Key findings | The trial is designed to test whether a 9-week manualized mindful yoga intervention added to treatment as usual improves depression outcomes and cost-effectiveness compared with treatment as usual alone in young women with major depressive disorder, and to examine potential mechanisms such as rumination, negative self-evaluation, intolerance of uncertainty, interoceptive awareness, and dispositional mindfulness. No outcome results are reported in this abstract. |
Abstract
Objectives: Despite the gains made by current first-line interventions for major depressive disorder (MDD), modest rates of treatment response and high relapse indicate the need to augment existing interventions. Following theory and initial research indicating the promise of mindful yoga interventions (MYIs), this study examines mindful yoga as a treatment of MDD. METHODS/DESIGN: This randomized controlled trial uses a sample of young females (18-34 years) to examine the efficacy and cost-effectiveness of a 9-week manualized MYI added to treatment as usual (TAU) versus TAU alone. Primary outcome measures consist of clinician-administered (Hamilton Depression Rating Scale) and self-report (Depression-Anxiety-Stress Scales) measures of depression. Underlying mechanisms will be examined, including rumination, negative self-evaluation, intolerance of uncertainty, interoceptive awareness, and dispositional mindfulness. Assessments were conducted at preintervention and will be conducted at postintervention, 6-, and 12-month follow up.
Results: = 9.36).
Conclusion: This trial will provide important information regarding the benefits of adding yoga-based interventions to TAU for young women with MDD and the mechanisms through which such benefits may occur.
Comparable studies
Other randomized controlled trials on depression, most cited first.
Citations in the library
Cited by 3
- The effectiveness of mindfulness yoga on patients with major depressive disorder: a systematic review and meta-analysis of randomized controlled trials. BMC Complementary Medicine and Therapies September 8, 2023
- Exploring young women's experiences of a mindful yoga intervention for depression in the Netherlands: Qualitative analysis of positive and negative effects British Journal of Clinical Psychology September 17, 2025
- Mindful yoga intervention as add-on to treatment as usual for young women with major depressive disorder: Results from a randomized controlled trial. Journal of Consulting and Clinical Psychology December 2022
Cites 12
- Using Self-Report Assessment Methods to Explore Facets of Mindfulness Assessment January 27, 2006
- Mindfulness: A proposed operational definition. Clinical Psychology Science and Practice 2004
- Prevention of relapse/recurrence in major depression by mindfulness-based cognitive therapy. Journal of Consulting and Clinical Psychology 2000
- Interoception, contemplative practice, and health Frontiers in Psychology June 9, 2015
- Mindfulness-based cognitive therapy as a treatment for chronic depression: A preliminary study Behaviour Research and Therapy February 13, 2009
and 7 more in the library