What works best for whom? Cognitive Behavior Therapy and Mindfulness-Based Cognitive Therapy for depressive symptoms in patients with diabetes.
K Annika Tovote, Maya J. Schroevers, Evelien Snippe, Paul M G Emmelkamp, Thera P Links, Robbert Sanderman, Joke Fleer
PLoS One October 5, 2019 DOI: 10.1371/journal.pone.0179941 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Randomized controlled trial Peer reviewed |
|---|---|
| Sample size | 91 |
| Population | Adult outpatients with type 1 or type 2 diabetes and comorbid depressive symptoms (BDI-II ≥ 14) |
| Interventions | Cognitive Behavior Therapy (CBT) Mindfulness-Based Cognitive Therapy (MBCT) |
| Duration | 8-week intervention, 9-month follow-up (1-year follow-up) |
| Measures | BDI-II |
| Topics | Meditation |
| Key findings | Education was the only factor that differentially predicted immediate symptom change: at post-treatment, individuals with higher educational attainment responded better to MBCT than to CBT, but this effect was not apparent at 9-month follow-up. The authors report no variables that robustly differentially predicted effectiveness of CBT versus MBCT, concluding both are accessible, effective interventions for depressive symptoms in broad diabetes populations. |
Abstract
Cognitive Behavior Therapy (CBT) and Mindfulness-Based Cognitive Therapy (MBCT) have shown to be effective interventions for treating depressive symptoms in patients with diabetes. However, little is known about which intervention works best for whom (i.e., moderators of efficacy). The aim of this study was to identify variables that differentially predicted response to either CBT or MBCT (i.e., prescriptive predictors).The sample consisted of 91 adult outpatients with type 1 or type 2 diabetes and comorbid depressive symptoms (i.e., BDI-II ≥ 14) who were randomized to either individual 8-week CBT (n = 45) or individual 8-week MBCT (n = 46). Patients were followed for a year and depressive symptoms were measured at pre-treatment, post-treatment, and at 9-months follow-up. The predictive effect of demographics, depression related characteristics, and disease specific characteristics on change in depressive symptoms was assessed by means of hierarchical regression analyses.Analyses showed that education was the only factor that differentially predicted a decrease in depressive symptoms directly after the interventions. At post-treatment, individuals with higher educational attainment responded better to MBCT, as compared to CBT. Yet, this effect was not apparent at 9-months follow-up.This study did not identify variables that robustly differentially predicted treatment effectiveness of CBT and MBCT, indicating that both CBT and MBCT are accessible interventions that are effective for treating depressive symptoms in broad populations with diabetes. More research is needed to guide patient-treatment matching in clinical practice.
Comparable studies
Other randomized controlled trials on meditation, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Alterations in Brain and Immune Function Produced by Mindfulness Meditation Healthy employees in a work environment | 2003 | Randomized controlled trial | n = 41 |
| Prevention of relapse/recurrence in major depression by mindfulness-based cognitive therapy. Recovered recurrently depressed patients | 2000 | Randomized controlled trial | n = 145 |
| Open hearts build lives: Positive emotions, induced through loving-kindness meditation, build consequential personal resources. Working adults | 2008 | Randomized controlled trial | n = 139 |
| Short-term meditation training improves attention and self-regulation Undergraduate Chinese students | 2007 | Randomized controlled trial | n = 40 |
| Mindfulness-Based Cognitive Therapy for Depression: Replication and Exploration of Differential Relapse Prevention Effects. Recovered recurrently depressed patients | 2004 | Randomized controlled trial | n = 73 |
Citations in the library
Cited by 10
- Meditation for the primary and secondary prevention of cardiovascular disease. Cochrane Database of Systematic Reviews February 15, 2024
- Terapia cognitiva baseada em mindfulness no atendimento clínico individual de depressão SMAD Revista Eletrônica Saúde Mental Álcool e Drogas (Edição em Português) September 30, 2020
- Long-term treatment outcomes of mindfulness-based cognitive therapy for fatigue in patients with inflammatory bowel disease: Results of a randomized controlled trial. Journal of Psychosomatic Research December 1, 2024
- Mindfulness-Based Cognitive Therapy for Fatigue in Patients with Inflammatory Bowel Disease: Results of a Randomized Controlled Trial Mindfulness 2023
- Predictive Factors of Response to Mindfulness-Based Cognitive Therapy (Mbct) for Patients with Depressive Symptoms: The Machine Learning’s Point of View OBM Integrative and Complementary Medicine December 28, 2022
and 5 more in the library
Cites 9
- Prevention of relapse/recurrence in major depression by mindfulness-based cognitive therapy. Journal of Consulting and Clinical Psychology 2000
- Mindfulness-Based Cognitive Therapy for Depression: Replication and Exploration of Differential Relapse Prevention Effects. Journal of Consulting and Clinical Psychology 2004
- Does Mindfulness-Based Cognitive Therapy benefit all people with diabetes and comorbid emotional complaints equally? Moderators in the DiaMind trial. Journal of Psychosomatic Research December 2016
- Mindfulness-based cognitive therapy vs cognitive behaviour therapy as a treatment for non-melancholic depression. Journal of Affective Disorders November 20, 2010
- A randomized pilot study of mindfulness-based cognitive therapy and group cognitive-behavioral therapy for young adults with social phobia. Scandinavian Journal of Psychology October 2010
and 4 more in the library