Smartphone Mindfulness Intervention Reduces Anxiety Symptoms and Perceived Stress in Autistic Adults: A Randomized Controlled Trial

A six-week app-based mindfulness intervention reduced anxiety and perceived stress in autistic adults. In a randomized controlled trial with 89 participants, those who used a customized version of the Healthy Minds Program app showed significant decreases in anxiety and stress compared to a wait-list control group, with medium to large effect sizes. Benefits extended to reduced negative affect and increased trait mindfulness, and were maintained six weeks after the intervention ended. The findings demonstrate that a remote, self-guided mindfulness program is both feasible and effective for this population, offering an accessible alternative to in-person treatment.

Study at a glance

Abstract

Abstract Objectives In-person mindfulness-based interventions (MBIs) have been shown to decrease symptoms of anxiety and stress in autistic adults, who often report high levels of these symptoms. Little is known about the effectiveness of remote MBIs for this population, which may be particularly useful given the common barriers autistic adults face in accessing in-person treatment. This study examined the feasibility and effectiveness of an app-based mindfulness intervention for autistic adults. Method This randomized controlled trial (RCT) examined whether a 6-week remote intervention, using a customized version of the Healthy Minds Program app, reduced symptoms of anxiety and perceived stress in 89 autistic adults. Participants were randomly assigned to either the mindfulness intervention or a wait-list control (WLC) group. The WLC group received the intervention after the RCT. Self-report measures of anxiety, perceived stress, positive and negative affect, and trait mindfulness were administered at several timepoints. Results The mindfulness group showed significant decreases in anxiety symptoms and perceived stress relative to the control group, with medium to large between-groups effect sizes ( η p 2 0.07 to 0.14). These benefits, as well as significant decreases in negative affect and increases in trait mindfulness, were replicated when the WLC group subsequently received the intervention, and were retained in both groups 6 weeks after conclusion of the intervention. Conclusions Results demonstrate both the feasibility and effectiveness of a remote mindfulness self-guided intervention for reducing perceived stress and anxiety symptoms in autistic adults. Future research can investigate the specific processes of how such an intervention exerts its effects. Preregistration ClinicalTrials.gov TRN: NCT05880498, 5/30/23, retrospectively registered.