Effect of mindfulness-based stress reduction in patients with acute myocardial infarction after successful primary percutaneous coronary intervention: a retrospective study.
Jun-Jie Gu, Xiao-Shan Tong, Sha-Sha Meng, Shu-Hui Xu, Jin-Yan Huang
BMC cardiovascular disorders June 23, 2023 DOI: 10.1186/s12872-023-03346-0 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Retrospective observational study Peer reviewed |
|---|---|
| Sample size | 122 |
| Population | Patients with acute myocardial infarction who underwent successful primary percutaneous coronary intervention |
| Interventions | Mindfulness-based stress reduction (MBSR) weekly health education |
| Duration | 8-week intervention; assessments at baseline, post-intervention, 1 month and 3 months after post-intervention |
| Measures | Hospital Anxiety and Depression Scale (HADS), Perceived Stress Scale (PSS), Perceived Social Support Scale (PSSS), 7-item Seattle Angina Questionnaire (SAQ-7), major adverse cardiovascular events (MACE), blood pressure (systolic, diastolic, mean arterial) |
| Topics | Meditation |
| Keywords | Acute myocardial infarction Mindfulness-based stress reduction |
| Key findings | Patients receiving 8-week MBSR showed lower blood pressure at later follow-ups, reduced anxiety and perceived stress, greater perceived social support, and better angina-related quality of life than those receiving health education. The control group had a higher total major adverse cardiovascular event rate (26.23% vs. 9.84%). The authors propose MBSR may be a beneficial adjunctive treatment after primary percutaneous coronary intervention. |
Abstract
This study aimed to examine the effects of mindfulness-based stress reduction (MBSR) in patients with acute myocardial infarction (AMI) after primary percutaneous coronary intervention (PPCI). A retrospective study was conducted with data collected from AMI patients who underwent successful PPCI. The study included 61 cases that received 8-week MBSR intervention (MBSR group) and 61 cases that received weekly health education (control group) over the same period. Outcome measures, including hemodynamic parameters, psychosocial characteristics [Hospital Anxiety and Depression Scale (HADS), Perceived Stress Scale (PSS), Perceived Social Support Scale (PSSS)], health-related quality of life [HRQoL, 7-item Seattle Angina Questionnaire (SAQ-7)], and major adverse cardiovascular events (MACE), were assessed at baseline (T1), post-intervention (T2), 1 month after the post-intervention (T3) and 3 months after the post-intervention (T4). Compared to the control group, the MBSR group showed improvements in blood pressure, specifically in systolic blood pressure (SBP) at T4, and diastolic blood pressure (DBP) at T3 and T4, and mean arterial blood pressure (MABP) at T3 and T4. Additionally, the MBSR group had lower scores of anxiety and perceived stress (HADS, PSS) and higher scores of perceived social support (PSSS) after the intervention. Furthermore, the MBSR group had higher scores on the SAQ-7 at all measurement points. The control group had a significantly higher total MACE rate compared to the MBSR group (26.23% vs. 9.84%). This study provides support for the potential benefits of MBSR as an adjunctive treatment for AMI patients undergoing PPCI.
Comparable studies
Other observational and cohort studies on meditation, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Using Self-Report Assessment Methods to Explore Facets of Mindfulness Undergraduate students | 2006 | Observational cohort | |
| Effectiveness of a meditation-based stress reduction program in the treatment of anxiety disorders Patients with generalized anxiety disorder or panic disorder with or without agoraphobia | 1992 | Observational cohort | n = 22 |
| Meditation experience is associated with increased cortical thickness Participants with extensive Insight meditation experience and matched controls | 2005 | Observational cohort | n = 20 |
| Meditation experience is associated with differences in default mode network activity and connectivity Experienced meditators and matched meditation-naive controls | 2011 | Observational cohort | |
| Long-term meditators self-induce high-amplitude gamma synchrony during mental practice Long-term Buddhist practitioners and controls | 2004 | Observational cohort |
Citations in the library
Cited by 3
- Effectiveness of Mindfulness Therapy as a Complement to Pharmacological Treatment in the Control of Blood Pressure in Hypertensive Adults: A Quasi-Experimental Study in Lima, Peru. Public health nursing (Boston, Mass.) 2025
- Yoga and Mindfulness-Based Rehabilitation After Myocardial Infarction: A Systematic Review. Healthcare April 21, 2026
- The impact of guided meditations and mindfulness on blood pressure regulation: analyzing the physiological impact of mental health techniques on cardiac biomarkers. Cogent Mental Health July 22, 2025
Cites 13
- Mindfulness-Based Stress Reduction vs Escitalopram for the Treatment of Adults With Anxiety Disorders: A Randomized Clinical Trial. JAMA Psychiatry January 1, 2023
- Mindfulness-Based Stress Reduction for Coronary Artery Disease Patients: Potential Improvements in Mastery and Depressive Symptoms. Journal of clinical psychology in medical settings September 2022
- Towards a mechanistic understanding of mindfulness-based stress reduction (MBSR) using an RCT neuroimaging approach: Effects on regulating own stress in social and non-social situations. Neuroimage July 1, 2022
- Effect of Mindfulness-Based Stress Reduction on the Well-Being, Burnout and Stress of Italian Healthcare Professionals during the COVID-19 Pandemic Journal of Clinical Medicine May 31, 2022
- The Effects of Mindfulness-Based Stress Reduction on Trauma in Victims of Gun Violence: a Pilot Study. Mindfulness 2022
and 8 more in the library