Yoga and Mindfulness-Based Rehabilitation After Myocardial Infarction: A Systematic Review.
Chiara Bianchi, Laura Rotondo, Claudio Bersani, Rita Pavasini, Federico Marchini, Serena Caglioni, Andrea Raisi, Gianluca Campo, Elisabetta Tonet
Healthcare April 21, 2026 DOI: 10.3390/healthcare14081106 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Systematic review Randomized Peer reviewed |
|---|---|
| Population | Adults following myocardial infarction |
| Interventions | Yoga-based cardiac rehabilitation mindfulness-based interventions |
| Topics | Meditation |
| Keywords | Myocardial infarction Rehabilitation Yoga Lifestyle |
| Key findings | The authors conclude that yoga- and mindfulness-based interventions appear to be promising complementary strategies in post-myocardial infarction care, with yoga-based cardiac rehabilitation possibly improving self-rated health, psychological well-being, and return to daily activities, and mindfulness-based interventions associated with reduced anxiety and perceived stress, improved blood pressure control, enhanced social support, and better health-related quality of life. One study reported fewer major adverse cardiac events (p = 0.032). Heterogeneity in protocols, outcomes, and designs limited direct comparisons. |
Abstract
Background: Psychological distress, autonomic dysregulation, and unhealthy lifestyle behaviors are common after myocardial infarction (MI) and negatively affect cardiovascular outcomes. In recent years, integrative mind-body interventions, such as yoga and mindfulness-based approaches, have gained increasing attention as adjuncts to conventional cardiac rehabilitation (CR) programs. However, evidence regarding their effectiveness in post-MI populations remains fragmented.
Objective: This systematic review aimed to synthesize the available evidence on the effects of yoga- and mindfulness-based interventions in patients following myocardial infarction.
Methods: A systematic literature search was conducted across major electronic databases to identify randomized controlled trials and observational studies evaluating yoga- or mindfulness-based interventions in post-MI patients. Eligible studies included adult MI populations. Study selection and quality assessment were performed according to predefined criteria.
Results: The 10 included studies suggest that yoga-based cardiac rehabilitation programs may provide benefits beyond standard care, particularly in terms of self-rated health, psychological well-being, and return to pre-infarction daily activities. Mindfulness-based interventions were associated with reductions in anxiety and perceived stress, improvements in blood pressure control, enhanced social support, and better health-related quality of life. Several studies also reported favorable effects on autonomic balance and stress-related physiological markers. Finally, a study reported benefits in terms of MACE (p = 0.032). However, heterogeneity in intervention protocols, outcome measures, and study designs limited direct comparisons across studies.
Conclusions: Yoga and mindfulness-based interventions appear to be promising complementary strategies in post-MI care.
Comparable studies
Other systematic reviews and meta-analyses on meditation, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Meditation Programs for Psychological Stress and Well-being Diverse adult clinical populations | 2014 | Meta-analysis | n = 3,515 |
| Mindfulness-Based Stress Reduction for Stress Management in Healthy People: A Review and Meta-Analysis Healthy subjects | 2009 | Systematic review and meta-analysis | |
| The psychological effects of meditation: A meta-analysis. Nonclinical groups of adult meditators | 2012 | Meta-analysis | n = 163 |
| Efficacy of Mindfulness-Based Cognitive Therapy in Prevention of Depressive Relapse Adults with recurrent depression in full or partial remission | 2016 | Meta-analysis of individual patient data from randomized controlled trials | n = 1,258 |
| Mindfulness‐Based Stress Reduction and Mindfulness‐Based Cognitive Therapy – a systematic review of randomized controlled trials | 2011 | Systematic review |
Citations in the library
Cites 10
- Mindfulness‐Based Stress Reduction and Mindfulness‐Based Cognitive Therapy – a systematic review of randomized controlled trials Acta Psychiatrica Scandinavica April 28, 2011
- Web-Based Mindfulness Intervention in Heart Disease: A Randomized Controlled Trial PLoS One December 7, 2015
- The effectiveness of mindfulness yoga on patients with major depressive disorder: a systematic review and meta-analysis of randomized controlled trials. BMC Complementary Medicine and Therapies September 8, 2023
- Brief Mindfulness-Based Cognitive Therapy in Women With Myocardial Infarction: Results of a Multicenter Randomized Controlled Trial. JACC. Advances February 1, 2025
- Effect of mindfulness-based stress reduction in patients with acute myocardial infarction after successful primary percutaneous coronary intervention: a retrospective study. BMC cardiovascular disorders June 23, 2023
and 5 more in the library