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Yoga and Mindfulness-Based Rehabilitation After Myocardial Infarction: A Systematic Review.

Chiara Bianchi, Laura Rotondo, Claudio Bersani, Rita Pavasini, Federico Marchini, Serena Caglioni, Andrea Raisi, Gianluca Campo, Elisabetta Tonet

Healthcare April 21, 2026 DOI: 10.3390/healthcare14081106 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Systematic review Randomized Peer reviewed
Population Adults following myocardial infarction
Interventions Yoga-based cardiac rehabilitation mindfulness-based interventions
Topics Meditation
Keywords Myocardial infarction Rehabilitation Yoga Lifestyle
Key findings The authors conclude that yoga- and mindfulness-based interventions appear to be promising complementary strategies in post-myocardial infarction care, with yoga-based cardiac rehabilitation possibly improving self-rated health, psychological well-being, and return to daily activities, and mindfulness-based interventions associated with reduced anxiety and perceived stress, improved blood pressure control, enhanced social support, and better health-related quality of life. One study reported fewer major adverse cardiac events (p = 0.032). Heterogeneity in protocols, outcomes, and designs limited direct comparisons.

Abstract

Background: Psychological distress, autonomic dysregulation, and unhealthy lifestyle behaviors are common after myocardial infarction (MI) and negatively affect cardiovascular outcomes. In recent years, integrative mind-body interventions, such as yoga and mindfulness-based approaches, have gained increasing attention as adjuncts to conventional cardiac rehabilitation (CR) programs. However, evidence regarding their effectiveness in post-MI populations remains fragmented.

Objective: This systematic review aimed to synthesize the available evidence on the effects of yoga- and mindfulness-based interventions in patients following myocardial infarction.

Methods: A systematic literature search was conducted across major electronic databases to identify randomized controlled trials and observational studies evaluating yoga- or mindfulness-based interventions in post-MI patients. Eligible studies included adult MI populations. Study selection and quality assessment were performed according to predefined criteria.

Results: The 10 included studies suggest that yoga-based cardiac rehabilitation programs may provide benefits beyond standard care, particularly in terms of self-rated health, psychological well-being, and return to pre-infarction daily activities. Mindfulness-based interventions were associated with reductions in anxiety and perceived stress, improvements in blood pressure control, enhanced social support, and better health-related quality of life. Several studies also reported favorable effects on autonomic balance and stress-related physiological markers. Finally, a study reported benefits in terms of MACE (p = 0.032). However, heterogeneity in intervention protocols, outcome measures, and study designs limited direct comparisons across studies.

Conclusions: Yoga and mindfulness-based interventions appear to be promising complementary strategies in post-MI care.

Comparable studies

Other systematic reviews and meta-analyses on meditation, most cited first.

Study Year Design Participants
Meditation Programs for Psychological Stress and Well-being Diverse adult clinical populations 2014 Meta-analysis n = 3,515
Mindfulness-Based Stress Reduction for Stress Management in Healthy People: A Review and Meta-Analysis Healthy subjects 2009 Systematic review and meta-analysis
The psychological effects of meditation: A meta-analysis. Nonclinical groups of adult meditators 2012 Meta-analysis n = 163
Efficacy of Mindfulness-Based Cognitive Therapy in Prevention of Depressive Relapse Adults with recurrent depression in full or partial remission 2016 Meta-analysis of individual patient data from randomized controlled trials n = 1,258
Mindfulness‐Based Stress Reduction and Mindfulness‐Based Cognitive Therapy – a systematic review of randomized controlled trials 2011 Systematic review

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