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Mindfulness-Based Stress Reduction for Coronary Artery Disease Patients: Potential Improvements in Mastery and Depressive Symptoms.

Oskar Lundgren, Peter Garvin, Lennart Nilsson, Viktor Tornerefelt, Gerhard Andersson, Margareta Kristenson, Lena Jonasson

Journal of clinical psychology in medical settings September 2022 DOI: 10.1007/s10880-021-09822-z (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Feasibility study Peer reviewed
Sample size 79
Population Coronary artery disease patients with elevated depressive symptoms, plus a reference group of 108 CAD patients
Intervention Mindfulness-based stress reduction (MBSR)
Duration 8-week MBSR course; 12-month follow-up
Topics Depression Meditation
Keywords Coronary artery disease Mastery Myocardial infarction
Registration NCT03340948
Key points MBSR was feasible for CAD patients with elevated depressive symptoms: 30% accepted and 20% completed the course. Depressive symptoms decreased immediately after the course and the improvement remained at 12 months, when Mastery scores increased. A reference group of 108 CAD patients showed no significant changes in depressive symptoms or Mastery.

Abstract

Depressive symptoms after coronary events are associated with a worse prognosis. When changing the focus from psychopathology towards a resilience framework, treatments such as mindfulness meditation could offer novel ways to address psychological distress among coronary artery disease (CAD) patients. We studied the feasibility of mindfulness-based stress reduction (MBSR) for CAD patients with depressive symptoms. Seventy-nine CAD patients with elevated depressive symptoms were invited to an 8-week MBSR course. Twenty-four patients (30%) accepted and 16 (20%) completed MBSR. Depressive symptoms decreased immediately after the course (p = .006). After 12 months, this improvement remained, and Mastery scores increased (p = .005). A reference group of 108 CAD patients did not show any significant changes in depressive symptoms or Mastery between 1 and 12 months after a coronary event. MBSR thus appears to be a feasible alternative for CAD patients with elevated depressive symptoms. Future studies are warranted to study if MBSR can improve psychological functioning in CAD patients.Clinicaltrials.gov (Registration Number: NCT03340948).

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