Positive Affect as a Transdiagnostic Target for Reducing Adolescent Depression & Suicide Risk: Do Mindfulness, Savoring, & Gratitude Help?
Natalia Macrynikola, Jackson Doerr, Shirley Yen
Journal des adolescens June 3, 2026 DOI: 10.1002/jad.70189 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Pilot randomized controlled trial Peer reviewed |
|---|---|
| Sample size | 52 |
| Population | Adolescents ages 12-18 hospitalized for suicide-related reasons in the northeastern U.S. (62% female, 31% male, 8% transgender) |
| Intervention | savoring |
| Topics | Depression Meditation |
| Key findings | Increases in positive affect predicted lower depressive symptoms (B = 1.00) and lower suicide ideation (B = 3.04) at follow-up. Mindfulness and savoring increases predicted lower depressive symptoms and, for savoring, lower suicide ideation; gratitude was only marginally associated with depressive symptoms and not with suicide ideation. The authors argue positive affect is a transdiagnostic target for adolescent depression and suicide risk. |
Abstract
Introduction: Despite its known contribution to adolescent depression and suicide risk, low positive affect (PA) remains underemphasized in clinical interventions, with limited evidence on how to best enhance it. Using data from a pilot randomized controlled trial of a brief PA-enhancing intervention for high-risk youth, we hypothesized that increases in PA over the intervention period would prospectively predict lower depressive symptoms and suicide ideation (SI). We also hypothesized that increases in mindfulness, savoring, and gratitude would prospectively predict higher PA and lower depressive symptoms and SI.
Methods: Participants were 52 adolescents, ages 12-18 (62% female, 31% male, 8% transgender) hospitalized for suicide-related reasons in the northeastern U.S.
Results: PA increases (using an anhedonia measure, where lower scores reflect greater PA) predicted lower T2 depressive symptoms, B = 1.00, p < 0.01, and lower T2 SI, B = 3.04, p < 0.01. Mindfulness increases predicted lower T2 depressive symptoms, B = -14.55, p < 0.01, and were marginally associated with lower T2 SI, B = -23.93, p = 0.08. Savoring increases predicted lower T2 depressive symptoms, B = -3.68, p < 0.05, and lower T2 SI, B = -17.50, p < 0.01. Gratitude increases were marginally associated with T2 depressive symptoms, B = -0.68, p = 0.07, but not T2 SI. Mindfulness, savoring, and gratitude increases were significant predictors of higher T2 PA. All analyses adjusted for T1 scores.
Conclusion: Findings support PA as a transdiagnostic target for adolescent depression and suicide risk. When developmentally tailored, mindfulness, savoring, and gratitude strategies may help enhance PA. Larger studies are needed to confirm these preliminary findings.
Comparable studies
Other randomized controlled trials on depression, most cited first.
Citations in the library
Cites 8
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- The effect of mindfulness-based cognitive therapy on suicidal thoughts and interleukin-6 levels in depressed adolescents. Journal of Affective Disorders October 1, 2025
- Mindful awareness and resilience skills for adolescents (MARS-A): a mixed-methods study of a mindfulness-based intervention for a heterogeneous adolescent clinical population. International journal of adolescent medicine and health February 1, 2024
- Self-compassion, Positive and Negative Affect and Social Avoidance among Adolescence: Mediating Role of Mindfulness. Clinical practice and epidemiology in mental health : CP & EMH 2023
and 3 more in the library