MDMA induced hyperthermia: report of a fatality and review of current therapy.
K J Dar, M E McBrien
Intensive care medicine September 1996 DOI: 10.1007/bf02044131 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Case report Peer reviewed |
|---|---|
| Sample size | 1 |
| Population | A person who died after ingesting MDMA |
| Intervention | MDMA |
| Topics | MDMA |
| Key findings | The authors report a fatality associated with MDMA ingestion and note that MDMA toxicity is characterized by hyperthermia, coagulopathy, rhabdomyolysis, and renal failure. They also briefly review the literature on MDMA-induced hyperthermia. |
Abstract
Ingestion of 3,4-methylene dioxymethamphetamine (MDMA), commonly known as "Ecstasy", can produce toxicity that is characterised by hyperthermia, coagulopathy, rhabdomyolysis and renal failure. We report a fatality associated with MDMA ingestion and briefly review the current literature on MDMA-induced hyperthermia.
Comparable studies
Other case reports and case series on MDMA, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| 'Eve' and 'Ecstasy'. A report of five deaths associated with the use of MDEA and MDMA Individuals whose deaths were associated with MDMA or MDEA use | 1987 | Case series | n = 5 |
| Pathology of deaths associated with "ecstasy" and "eve" misuse. Young white men aged 20 to 25 who died after using ring-substituted amphetamines (MDMA... | 1996 | Case series | n = 7 |
| 'Eve' and 'Ecstasy' Individuals who died after using MDMA or MDEA | 1987 | Case series | n = 5 |
| A Method of Conducting Therapeutic Sessions with MDMA Clients with clear therapeutic purpose, excluding those with serious functional... | 1998 | Case study | n = 2 |
| Diversity of Psychopathology Associated with use of 3,4-Methylenedioxymethamphetamine (‘Ecstasy’) Psychiatric patients presenting between 1990 and 1992 whose symptoms developed in the... | 1994 | Case series | n = 13 |
Citations in the library
Cited by 27
- Small Changes in Ambient Temperature Cause Large Changes in 3,4-Methylenedioxymethamphetamine (MDMA)-Induced Serotonin Neurotoxicity and Core Body Temperature in the Rat Journal of Neuroscience July 1, 1998
- A Comprehensive Review of MDMA and GHB: Two Common Club Drugs Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy December 1, 2001
- An Exploration of the History and Controversies Surrounding MDMA and MDA Journal of Psychoactive Drugs September 1, 2001
- Ecstasy (MDMA) Deaths in New York City: A Case Series and Review of the Literature Journal of Forensic Sciences 2002
- Carvedilol reverses hyperthermia and attenuates rhabdomyolysis induced by 3,4-methylenedioxymethamphetamine (MDMA, Ecstasy) in an animal model* Critical Care Medicine June 1, 2005
and 22 more in the library
Cites 4
- Multiple Severe Complications From Recreational Ingestion of MDMA ('Ecstasy') JAMA August 14, 1987
- Methylenedioxymethamphetamine-induced hyperthermia and neurotoxicity are independently mediated by 5-HT2 receptors Brain Research October 1, 1990
- Toxicity and deaths from 3,4-methylenedioxymethamphetamine ("ecstasy"). The Lancet August 15, 1992
- An overdose of ecstasy. A role for dantrolene. Anaesthesia August 1992