An overdose of ecstasy. A role for dantrolene.
C Singarajah, N G Lavies
Anaesthesia August 1992 DOI: 10.1111/j.1365-2044.1992.tb02391.x (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Case study Case report Peer reviewed |
|---|---|
| Sample size | 1 |
| Population | A patient who overdosed on MDMA |
| Intervention | Dantrolene |
| Topics | MDMA |
| Key findings | An MDMA overdose resulted in convulsions, hyperthermia, hyperkalaemia, and rhabdomyolysis, and the authors describe managing the patient with dantrolene as part of treatment. |
Abstract
An overdose of the semisynthetic, hallucinogenic amphetamine 3,4-methylenedioxymethamphetamine resulted in convulsions, hyperthermia, hyperkalaemia and rhabdomyolysis. The patient's management, which included the use of dantrolene, is discussed.
Comparable studies
Other case reports and case series on MDMA, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| 'Eve' and 'Ecstasy'. A report of five deaths associated with the use of MDEA and MDMA Individuals whose deaths were associated with MDMA or MDEA use | 1987 | Case series | n = 5 |
| Pathology of deaths associated with "ecstasy" and "eve" misuse. Young white men aged 20 to 25 who died after using ring-substituted amphetamines (MDMA... | 1996 | Case series | n = 7 |
| 'Eve' and 'Ecstasy' Individuals who died after using MDMA or MDEA | 1987 | Case series | n = 5 |
| A Method of Conducting Therapeutic Sessions with MDMA Clients with clear therapeutic purpose, excluding those with serious functional... | 1998 | Case study | n = 2 |
| Diversity of Psychopathology Associated with use of 3,4-Methylenedioxymethamphetamine (‘Ecstasy’) Psychiatric patients presenting between 1990 and 1992 whose symptoms developed in the... | 1994 | Case series | n = 13 |
Citations in the library
Cited by 20
- MDMA (Ecstasy) and the Rave: A Review Pediatrics October 1, 1997
- Review article: mechanisms and management of hepatotoxicity in ecstasy (MDMA) and amphetamine intoxications Alimentary Pharmacology & Therapeutics February 1, 1999
- A Comprehensive Review of MDMA and GHB: Two Common Club Drugs Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy December 1, 2001
- Fatal multi-organ failure after suicidal overdose with MDMA, `Ecstasy': case report and review of the literature Human & Experimental Toxicology February 1, 1999
- Hyperthermia associated with 3,4‐methylenedioxyethamphetamine (‘Eve’) Anaesthesia June 1, 1993
and 15 more in the library
Cites 6
- Hallucinogenic Amphetamine Selectively Destroys Brain Serotonin Nerve Terminals Science September 6, 1985
- 'Eve' and 'Ecstasy'. A report of five deaths associated with the use of MDEA and MDMA JAMA March 27, 1987
- 'Eve' and 'Ecstasy' JAMA March 27, 1987
- Can Drugs Be Used to Enhance the Psychotherapeutic Process? American Journal of Psychotherapy July 1, 1986
- Multiple Severe Complications From Recreational Ingestion of MDMA ('Ecstasy') JAMA August 14, 1987
and 1 more in the library