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Effects of Short-Term Mindfulness Combined with Acupressure on Preoperative Emotional Status in Patients Undergoing Heart Valve Replacement: A Randomized Controlled Study

Shiqiang Xiang, Zhaoyun Yang, Meijie Deng, Lianmei Chen, Qian Chen, Ruixia Wang

Acupuncture & Electro-Therapeutics Research: International Journal of Integrated Medicine June 2, 2026 DOI: 10.1177/03601293261456739 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Randomized controlled trial Peer reviewed
Sample size 62
Population Patients admitted to the Department of Cardiac Surgery of a tertiary hospital in Guizhou for heart valve replacement, May to October 2024
Interventions Short-term mindfulness (STM) acupressure
Measures Amsterdam Preoperative Anxiety and Information Scale (APAIS), Self-Rating Depression Scale (SDS), Five Facet Mindfulness Questionnaire (FFMQ), heart rate (HR), systolic blood pressure (SBP), diastolic blood pressure (DBP)
Topics Meditation
Key findings Short-term mindfulness combined with acupressure, added to routine psychological care, was associated with lower preoperative anxiety and depressive symptoms, higher mindfulness levels, and lower systolic blood pressure, diastolic blood pressure, and heart rate compared with placebo in patients undergoing heart valve replacement. The authors describe these as preliminary findings requiring larger samples and longer follow-up.

Abstract

Objective: This study aimed to investigate the effects of a combined regimen of short-term mindfulness (STM) and acupressure on preoperative mood and physiological responses in patients undergoing heart valve replacement (HVR).

Methods: A randomized controlled study was conducted in 62 patients admitted to the Department of Cardiac Surgery of a tertiary hospital in Guizhou from May to October 2024. Patients were randomly assigned to an intervention group or a control group, with 31 patients in each group. The intervention group received routine psychological care plus STM combined with acupressure, while the control group received routine psychological care plus a placebo intervention. Preoperative anxiety, depressive symptoms, and mindfulness level were assessed using the Amsterdam Preoperative Anxiety and Information Scale (APAIS), Self-Rating Depression Scale (SDS), and Five Facet Mindfulness Questionnaire (FFMQ), respectively. Heart rate (HR), systolic blood pressure (SBP), and diastolic blood pressure (DBP) were also recorded.

Results: Sixty patients completed the study. After the intervention, the intervention group had lower APAIS anxiety scores and SDS scores than the control group, and higher total FFMQ scores. Scores for observing, acting with awareness, non-judging, and non-reactivity were also higher in the intervention group. In addition, SBP, DBP, and HR were lower in the intervention group than in the control group (all p < 0.05).

Conclusion: STM combined with acupressure may improve mindfulness level, relieve preoperative anxiety and depressive symptoms, and help stabilize BP and HR in patients undergoing HVR. These preliminary findings suggest that this combined intervention may be a feasible adjunctive preoperative supportive strategy, but further studies with larger samples and longer follow-up are needed to verify its clinical applicability.

Comparable studies

Other randomized controlled trials on meditation, most cited first.

Study Year Design Participants
Alterations in Brain and Immune Function Produced by Mindfulness Meditation Healthy employees in a work environment 2003 Randomized controlled trial n = 41
Prevention of relapse/recurrence in major depression by mindfulness-based cognitive therapy. Recovered recurrently depressed patients 2000 Randomized controlled trial n = 145
Open hearts build lives: Positive emotions, induced through loving-kindness meditation, build consequential personal resources. Working adults 2008 Randomized controlled trial n = 139
Short-term meditation training improves attention and self-regulation Undergraduate Chinese students 2007 Randomized controlled trial n = 40
Mindfulness-Based Cognitive Therapy for Depression: Replication and Exploration of Differential Relapse Prevention Effects. Recovered recurrently depressed patients 2004 Randomized controlled trial n = 73

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