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Selected Abstracts of Conference Presentation at the 2007 International Society for Neurofeedback and Research (ISNR) 15th Annual Conference, San Diego, California

Journal of Neurotherapy August 11, 2008 DOI: 10.1080/10874200802219921 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Observational cohort Peer reviewed
Sample size 8
Population Participants undergoing a Salvia divinorum experience
Duration 10-15 minutes post-experience recovery period
Measures EEG
Citations 3
Key findings Salvia-induced EEG changes were reversible and correlated with the end of altered states of consciousness. Alpha power was significantly reduced in 6 of 8 participants, with increases in delta, theta, and beta1 power in some. Effects returned toward baseline within 10-15 minutes post-experience.

Abstract

ResultsThe Salvia-induced shifts in EEG compared to the baseline signature were striking.The most consistent effects observed were: In 6 of 8 participants, Alpha power (9-10 Hz) was significantly reduced (M ¼ 63%, p < .04,twotailed correlated samples) and alpha spindling disorganized.In 4 participants, abundant large amplitude slow cortical potentials (SCPs) were recorded at many cortical sites.If SCPs were present during baseline, they increased in amplitude and frequency and were evident at more scalp sites during the Salvia experience.Intersubject Salvia effects varied considerably, consistent with individual baseline signatures.Some significant effects revealed: increased Delta power (2-4 Hz), increased Theta power (4-6 Hz ), and increased Beta1 power (14-16 Hz).Also, significant shifts in amplitude asymmetry, coherence, and phase maps were evident.Consistently observed for all participants, the EEG signature returned toward baseline values upon recovery (10-15 min post).That is, Salvia-induced shifts in EEG were reversible and correlated with a participant's report of ending the ASC and returning to ordinary consciousness. ConclusionsSalvia's short-acting and nontolerance buildup profile may find application in the broad interface between psychiatry, psychopharmacology, and herbal medicine.Salvia is currently being studied for its therapeutic antidepressive potential (Hanes, K.R.

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