An ETH-LAD trip with unfavourable consequences: A case report.
J. Nadler, Michaela J. Sommer, Annette Zschiesche, A. Stürzebecher, Christina Grumann, Volker Auwärter, Maren Hermanns‐clausen
British Journal of Clinical Pharmacology August 7, 2026 DOI: 10.1002/bcp.70776 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Case study Case report Peer reviewed |
|---|---|
| Sample size | 1 |
| Population | An adolescent patient |
| Duration | 17 days of hospitalization |
| Key findings | The first analytically confirmed ETH-LAD ingestion resulted in severe toxic effects, including persistent psychosis and metabolic disturbances, with a serum concentration of 38 ng/mL, requiring intensive care and 17 days of hospitalization before transfer to a psychiatric clinic. |
Abstract
Numerous analogues of the psychedelic and internationally controlled hallucinogen LSD have been described; however, only a limited number have been systematically investigated. This report presents the first case with an analytically confirmed ingestion of ETH-LAD (6-ethyl-6-nor-lysergic acid diethylamide), the N-ethyl derivative of LSD. An adolescent patient developed moderate to severe symptoms as acute aggression, agitation, unconsciousness, multiple traumatic injuries, metabolic disturbances and persistent psychosis following ETH-LAD ingestion and required intensive medical therapy with unexpected findings. The concentration of the hallucinogenic new psychoactive substance in serum was determined with 38 ng mL-1. After 17 days of hospitalization, the patient was transferred to a psychiatric clinic for further treatment. Physicians must be aware that ETH-LAD ingestion may, unlike LSD, lead to severe toxic effects, requiring intensive care.
Citations in the library
Cites 7
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