Pharmacokinetics and Concentration-Effect Relationship of Oral LSD in Humans
Patrick C. Dolder, Yasmin Schmid, Manuel Haschke, Katharina Rentsch, Matthias E. Liechti
The International Journal of Neuropsychopharmacology June 24, 2015 DOI: 10.1093/ijnp/pyv072 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Pharmacokinetic study Peer reviewed |
|---|---|
| Population | Healthy adults |
| Intervention | Lysergic acid diethylamide |
| Topics | LSD |
| Keywords | Pharmacokinetics Urine Pharmacology Active metabolite Oral administration Pharmacodynamics |
| Citations | 110 |
| Key points | LSD exhibits dose-proportional pharmacokinetics with a terminal half-life of 3.6 hours and effects lasting up to 12 hours. |
Abstract
These first data on the pharmacokinetics and concentration-effect relationship of oral lysergic acid diethylamide are relevant for further clinical studies and serve as a reference for the assessment of intoxication with lysergic acid diethylamide.