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Ayahuasca experiences in Uruguay: An interpretative phenomenological analysis of Neovegetalismo and Santo Daime

Ismael Apud, Juan Scuro, Frank Lozano Jara, Juan Ignacio Retta, Ignacio Carrera

Journal of Psychedelic Studies March 30, 2026 DOI: 10.1556/2054.2025.00496 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Qualitative study Peer reviewed
Sample size 44
Population Participants of a neovegetalismo group and Santo Daime Church in Uruguay
Intervention Ayahuasca
Topics Ayahuasca
Key findings Ayahuasca experiences differed by ritual context: neo-shamanic rituals yielded intense experiences with frequent corporal, emotional, sensorial, and personal themes, while Santo Daime rituals were gentler with lower frequencies of spiritual and transcendental themes. The authors suggest experiences are shaped by the interaction of the brew, ritual setting, and participants' mindset.

Abstract

Abstract Background This study presents the qualitative findings of interdisciplinary research exploring ayahuasca-induced experiences in two distinct groups in Uruguay: a neo-shamanic group rooted in the Peruvian vegetalismo tradition and a Santo Daime Church.

Aims: Using interpretative phenomenological analysis, the study examines similarities and differences in subjective experiences during a neo-shamanic ritual and a religious ritual ( n = 18).

Methods: Semi-structured in-depth interviews were conducted with 26 participants of a neovegetalismo group and with 18 participants of Santo Daime.

Results: Experiences in the neo-shamanic ritual were generally intense, with 145 coded segments categorized into six main themes. Corporal Experiences emerged as the most frequent (69%), followed by Emotional, Sensorial, and Personal Experiences (61% each one), Spiritual & Transcendental Experiences (50%), and Cognition & Volition (19%). In contrast, the Santo Daime ritual, characterized by dance and communal singing rather than deep introspection or visions, was described as gentler (42 coded segments). The most frequently reported themes were Corporal (50%), Emotional (44%), Personal (39%), Sensorial (28%), Spiritual & Transcendental (6%), and Cognition & Volition (1%).

Conclusions: Findings suggest that ayahuasca-induced experiences are shaped by the interaction between the brew, ritual setting, and participants' mindset, highlighting both recurrent and context-dependent experiential patterns.

Comparable studies

Other qualitative studies on ayahuasca, most cited first.

Study Year Design Participants
The antipodes Of the mind Indigenous people, shamans, members of different religious sects using Ayahuasca, and... 2002 Qualitative study
Drug Tourism or Spiritual Healing? Ayahuasca Seekers in Amazonia Westerners participating in an ayahuasca retreat in Amazonia 2005 Qualitative study
Therapeutic Effects of Ritual Ayahuasca Use in the Treatment of Substance Dependence—Qualitative Results Therapists, expert researchers, and individuals who underwent ayahuasca-assisted... 2014 Qualitative study n = 29
Nourishing the Spirit: Exploratory Research on Ayahuasca Experiences along the Continuum of Recovery from Eating Disorders Individuals previously diagnosed with an eating disorder 2017 Qualitative study n = 16
Exploring ayahuasca‐assisted therapy for addiction: A qualitative analysis of preliminary findings among an Indigenous community in Canada Indigenous adults in Canada who participated in ayahuasca-assisted ceremonial retreats 2019 Qualitative study n = 11

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