Self-Compassion and Resilience as Mediators of a 30-Day Internet-Delivered Mindfulness-Based Cognitive Therapy: A Pragmatic Open Trial
Paweł Holas, Jan Wardęszkiewicz
Research Square September 9, 2025 preprint DOI: 10.21203/rs.3.rs-7555045/v1 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Pragmatic two-arm open trial |
|---|---|
| Sample size | 190 |
| Population | Community sample of adults reporting emotional distress |
| Duration | 30-day program; baseline and post-intervention assessments |
| Topics | Meditation |
| Key findings | A brief, asynchronous iMBCT program reduced self-reported perceived stress, emotional distress, anxiety, and depression and increased self-compassion and resilience compared with a waiting-list control. Mediation analyses indicated that gains in self-compassion and resilience partially accounted for the reductions in stress and distress, explaining 18-32% of the total effect. High attrition (67%) and lack of follow-up limit conclusions about long-term effects and generalizability. |
Abstract
Abstract Objectives Emotional distress, encompassing stress, anxiety, and depression, is highly prevalent and associated with substantial personal and societal burden. While Mindfulness-Based Cognitive Therapy (MBCT) is an established intervention, its accessibility is often limited by program length, delivery format, and resource demands. Brief, minimally guided, internet-delivered MBCT (iMBCT) formats may offer a scalable alternative, but evidence for their effectiveness and mechanisms remains limited. This pragmatic two-arm open trial evaluated the feasibility and preliminary effects of a 30-day asynchronous iMBCT program in a community sample. The primary outcomes were reductions in perceived stress and emotional distress; secondary analyses examined whether self-compassion and resilience functioned as processes of change.
Methods: A total of 1,348 adults reporting emotional distress were allocated to either the iMBCT program or a waiting-list control (WLC). Due to high attrition, propensity score matching (PSM) was applied, yielding a final analytic sample of 190 individuals (91 iMBCT, 99 WLC). The intervention comprised six online MBCT sessions with audio-guided practices and psychoeducational materials.
Outcomes: (perceived stress, emotional distress, anxiety, depression, self-compassion, and resilience) were assessed at baseline and post-intervention. Analyses included mixed-model ANOVAs to evaluate group × time effects and mediation analyses (Hayes’ PROCESS, 10,000 bootstrap resamples) to test indirect effects through self-compassion and resilience.
Results: Compared with WLC, the iMBCT group showed significant reductions in perceived stress (η²p = .32, 95% CI [.21, .41]), emotional distress (η²p = .38, [.28, .47]), anxiety (η²p = .33, [.22, .42]), and depression (η²p = .34, [.24, .44]), alongside increases in self-compassion (η²p = .38, [.27, .47]) and resilience (η²p = .28, [.17, .37]). Mediation analyses indicated that improvements in self-compassion and resilience partially accounted for reductions in stress and distress, explaining 18–32% of the total effect across outcomes. The intervention experienced 67% attrition, and engagement metrics were not collected.
Conclusions: A brief, asynchronous iMBCT program can reduce self-reported stress, emotional distress, anxiety, and depression while enhancing self-compassion and resilience in a community sample. However, high attrition, reliance on self-report, and the absence of clinical diagnoses or follow-up limit generalizability and conclusions about long-term effects. Future studies should test such interventions in clinical populations, incorporate guided or synchronous elements to improve adherence, and collect objective engagement data to clarify dose–response relationships.
Comparable studies
Other non-randomized and open-label trials on meditation, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Mindfulness-Based Stress Reduction in Relation to Quality of Life, Mood, Symptoms of Stress, and Immune Parameters in Breast and Prostate Cancer Outpatients Early-stage breast and prostate cancer patients | 2003 | Pre-post intervention study | n = 59 |
| Exploring self‐compassion and empathy in the context of mindfulness‐based stress reduction (MBSR) Community sample | 2010 | Pre-post intervention study | |
| Mindfulness-Based Stress Reduction Lowers Psychological Distress In Medical Students Second-year medical students | 2003 | Prospective nonrandomized cohort-controlled study | n = 302 |
| Intensive meditation training, immune cell telomerase activity, and psychological mediators. Retreat participants and matched controls | 2011 | Controlled trial with wait-list control group | n = 60 |
| The Effectiveness of Mindfulness Training for Children with ADHD and Mindful Parenting for their Parents Children aged 8-12 with ADHD and their parents | 2011 | Within-group waitlist controlled trial | n = 22 |
Citations in the library
Cites 7
- The Empirical Status of Mindfulness-Based Interventions: A Systematic Review of 44 Meta-Analyses of Randomized Controlled Trials Perspectives on Psychological Science February 16, 2021
- Mindfulness‐based cognitive therapy for patients with chronic, treatment‐resistant depression: A pragmatic randomized controlled trial Depression and Anxiety August 8, 2018
- Effects of preventive online mindfulness interventions on stress and mindfulness: A meta-analysis of randomized controlled trials Preventive Medicine Reports March 9, 2017
- For Whom Does Mindfulness-Based Stress Reduction Work? Moderating Effects of Personality. Mindfulness 2017
- Has the science of mindfulness lost its mind? BJPsych Bulletin December 2016
and 2 more in the library