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Self-Compassion and Resilience as Mediators of a 30-Day Internet-Delivered Mindfulness-Based Cognitive Therapy: A Pragmatic Open Trial

Paweł Holas, Jan Wardęszkiewicz

Research Square September 9, 2025 preprint DOI: 10.21203/rs.3.rs-7555045/v1 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Pragmatic two-arm open trial
Sample size 190
Population Community sample of adults reporting emotional distress
Duration 30-day program; baseline and post-intervention assessments
Topics Meditation
Key findings A brief, asynchronous iMBCT program reduced self-reported perceived stress, emotional distress, anxiety, and depression and increased self-compassion and resilience compared with a waiting-list control. Mediation analyses indicated that gains in self-compassion and resilience partially accounted for the reductions in stress and distress, explaining 18-32% of the total effect. High attrition (67%) and lack of follow-up limit conclusions about long-term effects and generalizability.

Abstract

Abstract Objectives Emotional distress, encompassing stress, anxiety, and depression, is highly prevalent and associated with substantial personal and societal burden. While Mindfulness-Based Cognitive Therapy (MBCT) is an established intervention, its accessibility is often limited by program length, delivery format, and resource demands. Brief, minimally guided, internet-delivered MBCT (iMBCT) formats may offer a scalable alternative, but evidence for their effectiveness and mechanisms remains limited. This pragmatic two-arm open trial evaluated the feasibility and preliminary effects of a 30-day asynchronous iMBCT program in a community sample. The primary outcomes were reductions in perceived stress and emotional distress; secondary analyses examined whether self-compassion and resilience functioned as processes of change.

Methods: A total of 1,348 adults reporting emotional distress were allocated to either the iMBCT program or a waiting-list control (WLC). Due to high attrition, propensity score matching (PSM) was applied, yielding a final analytic sample of 190 individuals (91 iMBCT, 99 WLC). The intervention comprised six online MBCT sessions with audio-guided practices and psychoeducational materials.

Outcomes: (perceived stress, emotional distress, anxiety, depression, self-compassion, and resilience) were assessed at baseline and post-intervention. Analyses included mixed-model ANOVAs to evaluate group × time effects and mediation analyses (Hayes’ PROCESS, 10,000 bootstrap resamples) to test indirect effects through self-compassion and resilience.

Results: Compared with WLC, the iMBCT group showed significant reductions in perceived stress (η²p = .32, 95% CI [.21, .41]), emotional distress (η²p = .38, [.28, .47]), anxiety (η²p = .33, [.22, .42]), and depression (η²p = .34, [.24, .44]), alongside increases in self-compassion (η²p = .38, [.27, .47]) and resilience (η²p = .28, [.17, .37]). Mediation analyses indicated that improvements in self-compassion and resilience partially accounted for reductions in stress and distress, explaining 18–32% of the total effect across outcomes. The intervention experienced 67% attrition, and engagement metrics were not collected.

Conclusions: A brief, asynchronous iMBCT program can reduce self-reported stress, emotional distress, anxiety, and depression while enhancing self-compassion and resilience in a community sample. However, high attrition, reliance on self-report, and the absence of clinical diagnoses or follow-up limit generalizability and conclusions about long-term effects. Future studies should test such interventions in clinical populations, incorporate guided or synchronous elements to improve adherence, and collect objective engagement data to clarify dose–response relationships.

Comparable studies

Other non-randomized and open-label trials on meditation, most cited first.

Study Year Design Participants
Mindfulness-Based Stress Reduction in Relation to Quality of Life, Mood, Symptoms of Stress, and Immune Parameters in Breast and Prostate Cancer Outpatients Early-stage breast and prostate cancer patients 2003 Pre-post intervention study n = 59
Exploring self‐compassion and empathy in the context of mindfulness‐based stress reduction (MBSR) Community sample 2010 Pre-post intervention study
Mindfulness-Based Stress Reduction Lowers Psychological Distress In Medical Students Second-year medical students 2003 Prospective nonrandomized cohort-controlled study n = 302
Intensive meditation training, immune cell telomerase activity, and psychological mediators. Retreat participants and matched controls 2011 Controlled trial with wait-list control group n = 60
The Effectiveness of Mindfulness Training for Children with ADHD and Mindful Parenting for their Parents Children aged 8-12 with ADHD and their parents 2011 Within-group waitlist controlled trial n = 22

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