Evaluation of the effects of 12 weeks mindfulness-based stress reduction on glycemic control and mental health indices in women with diabetes mellitus type 2
Omid Nikkhah Ravari, Seyedeh Zeinab Mousavi, Anahita Babak
Advanced Biomedical Research November 4, 2020 DOI: 10.4103/abr.abr_133_20 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Randomized clinical trial Peer reviewed |
|---|---|
| Sample size | 108 |
| Population | Patients with type 2 diabetes mellitus in Isfahan, Iran |
| Intervention | Mindfulness-based stress reduction (MBSR) |
| Duration | 12-week intervention, assessment 13 weeks after start |
| Topics | Meditation |
| Keywords | Blood glucose Diabetes mellitus Type 2 Mental health Meditation a mindfulness |
| Key findings | MBSR significantly improved HbA1C, depression, anxiety, and stress scores compared to routine care, but the change in FBS was not significantly different between groups. |
Abstract
Background: Diabetes mellitus is one of the major health problems in the world. Stress and mental illnesses adversely affect glycemic control. In most patients, a multidisciplinary approach including physical activity, healthy diet, and stress management is required for glycemic control. Mindfulness-based stress reduction (MBSR) is a structured group program that reduces emotional distress through self-awareness and assuming the responsibility for individual choices, and results in increased effective health behaviors. Here, we aimed to evaluate the effects of mindfulness meditation on glycemic control and mental health in patients with type 2 diabetes.
Materials and Methods: This randomized clinical trial study was performed in 2018 in Isfahan city. A total number of 108 patients with diabetes mellitus type 2 were selected and allocated randomly to two groups, intervention (12 weeks MBSR program) and control (routine care). Depression, anxiety, and stress scores regarding to depression, anxiety, and stress Scale - 21 questionnaire and also amounts of fasting blood sugar (FBS) and hemoglobin A1C (HbA1C) were assessed and analyzed using independent t-test, paired t-test, Mann–Whitney U-test, and Chi-square, before and 13 weeks after educational programs.
Results: The means of HbA1C, FBS, and depression, anxiety, and stress scores improved significantly after intervention in the MBSR group. Except FBS levels, all outcome variable scores' mean change was significant between the two groups.
Conclusions: In general, this study revealed that mindfulness meditation could be helpful in improving the quality of mental health and lowering glycemic control indices in patients with type 2 diabetes mellitus.
Comparable studies
Other randomized controlled trials on meditation, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Alterations in Brain and Immune Function Produced by Mindfulness Meditation Healthy employees in a work environment | 2003 | Randomized controlled trial | n = 41 |
| Prevention of relapse/recurrence in major depression by mindfulness-based cognitive therapy. Recovered recurrently depressed patients | 2000 | Randomized controlled trial | n = 145 |
| Open hearts build lives: Positive emotions, induced through loving-kindness meditation, build consequential personal resources. Working adults | 2008 | Randomized controlled trial | n = 139 |
| Short-term meditation training improves attention and self-regulation Undergraduate Chinese students | 2007 | Randomized controlled trial | n = 40 |
| Mindfulness-Based Cognitive Therapy for Depression: Replication and Exploration of Differential Relapse Prevention Effects. Recovered recurrently depressed patients | 2004 | Randomized controlled trial | n = 73 |
Citations in the library
Cited by 9
- Meditation for the primary and secondary prevention of cardiovascular disease. Cochrane Database of Systematic Reviews February 15, 2024
- Mindfulness-based interventions for adults with type 2 diabetes mellitus: A systematic review and meta-analysis. Integrative Medicine Research June 1, 2025
- Effect of mindfulness-based intervention in patients with diabetes: a meta-analytic review. Psychology, Health & Medicine April 15, 2025
- Effects of Compassion Meditation on Psychological Status in Patients With Diabetes: A Pilot Randomized Controlled Trial Western Journal of Nursing Research June 29, 2026
- Meta-Analytic Insights Into Mindfulness Approaches for Depression and Diabetes Comorbidity Care. Diabetes Spectrum 2025
and 4 more in the library
Cites 6
- Meditation Programs for Psychological Stress and Well-being JAMA Internal Medicine January 6, 2014
- The Impact of Mindfulness-Based Stress Reduction on Emotional Wellbeing and Glycemic Control of Patients with Type 2 Diabetes Mellitus Journal of Diabetes Research June 28, 2018
- Mind-Body Interactions and Mindfulness Meditation in Diabetes. European endocrinology April 2018
- Reducing diabetes distress and improving self-management with mindfulness. Social Work in Health Care January 2018
- Effectiveness of Mindfulness-based interventions on physiological and psychological complications in adults with diabetes: A systematic review. Journal of Health Psychology July 2017
and 1 more in the library