Application of mindfulness-based stress reduction plan in post-stroke patients with mild depression.
Xiaofei Pang, Dong Qiu, Xiaowen He, Jiacheng Xu
Frontiers in Neurology 2025 DOI: 10.3389/fneur.2025.1629576 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Randomized controlled trial Peer reviewed |
|---|---|
| Sample size | 80 |
| Population | Patients with post-stroke mild depression |
| Interventions | Mindfulness-based stress reduction conventional intervention therapy |
| Duration | 8-week intervention |
| Topics | Depression Meditation |
| Keywords | Mild depression Mindfulness-based stress reduction Progressive resistance training Stroke |
| Key findings | Mindfulness-based stress reduction combined with conventional intervention therapy improved depression and cognitive outcomes more than conventional therapy alone in patients with post-stroke mild depression. |
Abstract
To explore the therapeutic effect of mindfulness-based stress reduction in patients with post-stroke mild depression. A total of 80 patients with mild depression after stroke received by our hospital from January 2023 to December 2023 were selected as the study subjects. Randomly divide the patients into two groups: 40 in the control group and 40 in the combination group. The control group received conventional intervention therapy, while the combination group was treated with a mindfulness-based stress reduction plan combined with conventional intervention therapy. Patients in both groups were treated for 8 weeks. The general information of patients in the two groups was statistically analyzed. Self-rating Depression Scale (SDS), Hamilton Depression Rating Scale (HAMD-17), Mini Mental State Examination (MMSE), Montreal Cognitive Assessment (MoCA) scores and inflammatory factors (including TNF-α, hs-CRP, IL-6) expression levels were used to evaluate the efficacy of patients before and after treatment, and the total effective rate was counted for the two groups. After treatment, compared with that before treatment, the HAMD-17 and SDS scores and inflammatory factor levels of patients in the control group and combination group were significantly decreased (all p < 0.05), while the MMSE and MoCA scores of patients in the control group and combination group were significantly increased (all p < 0.05). However, after treatment, the HAMD-17 and SDS scores and inflammatory factor levels of patients in the combination group were significantly lower than those in the control group (all p < 0.05). The scores of MMSE and MoCA were significantly higher than those in the control group (p < 0.05). In the treatment of stroke patients with mild depression, mindfulness-based stress reduction combined with conventional intervention therapy can improve the overall response rate compared with conventional intervention therapy alone and has a significant advantage in reducing depression.
Comparable studies
Other randomized controlled trials on depression, most cited first.
Citations in the library
Cites 2
- Effectiveness of Mindfulness-Based Stress Reduction as a Nondrug Preventive Intervention in Patients with Migraine: A Systematic Review with Meta-Analyses. Complementary Medicine Research 2023
- Effects of mindfulness-based stress reduction on sleep quality and mental health for insomnia patients: A meta-analysis. Journal of Psychosomatic Research May 21, 2020