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Meditation: From Self-Regulation to Ego-Dissolution

Ulrich Ott

The MIT Press eBooks December 16, 2025 DOI: 10.7551/mitpress/14600.003.0015 (opens in new tab) via OpenAlex

Summary

AI-generated from the abstract

Mystical experiences characterized by non-duality and ego dissolution are linked to specific brain activity patterns. Advanced meditators and psychedelic research reveal that during such experiences, the sense of self appears to dissolve. Neuroimaging and EEG studies identify neural correlates of these states. Factors like personality traits, meditation, and psychedelic substances can facilitate mystical experiences. Recent research with experienced meditators suggests both potential mental health benefits and risks associated with these experiences.

Study at a glance

Characteristics Review Peer reviewed
Keywords Work physics Identification biology Product mathematics
Key finding Neuroimaging and EEG studies with advanced meditators and psychedelic research provide insights into brain activity patterns accompanying mystical experiences where the ego seems to dissolve.

Abstract

elucidate the brain dynamics of non-ordinary experiences like "non-duality" and "egodissolution" by combining phenomenological assessment with modern brain imaging technology.In this chapter, I describe (1) typical features of mystical experiences (see glossary);(2) situations, personality traits, and methods that facilitate their occurrence; and (3) recent findings regarding their pos si ble neural correlates.Neuroimaging and electroencephalographic (EEG) studies with advanced meditators and experimental research using psychedelic substances provide new insights into patterns of brain activity that accompany those experiences, in which the ego seems to dissolve.A final section of the article addresses benefits and pos si ble risks of mystical experiences for mental health based on recent studies with advanced meditation prac ti tion ers.

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