A Case Review of the First Analytically Confirmed 25I-NBOMe-Related Death in Washington State.
L. M. Lowe, Brianna L Peterson, Fiona J. Couper
Journal of Analytical Toxicology October 1, 2015 DOI: 10.1093/jat/bkv092 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Case study Case report Peer reviewed |
|---|---|
| Sample size | 1 |
| Population | A 15-year-old male who died after ingesting 25I-NBOMe and mushrooms |
| Key findings | The death was attributed to combined intoxication with 25I-NBOMe and psilocin, with antemortem blood showing 0.76 ng/mL of 25I-NBOMe and hospital serum positive for THC and carboxy-THC. |
Abstract
This case was submitted to the Washington State Patrol Toxicology Laboratory in September 2014. A 15-year-old male went to a party where he ingested 25I-NBOMe and mushrooms. A short time later, he started to vomit and began seizing until he eventually passed out. Resuscitation efforts were made, but were unsuccessful. He was transported to a local hospital, where he died three days later of multi-system organ failure following cardiopulmonary arrest. The hospital admission samples were negative for ethanol and basic drugs and their metabolites. The hospital serum confirmed positive for delta-9-tetrahydrocannabinol (THC) and carboxy-THC at 4.1 and 83 ng/mL, respectively. On the basis of the case history, the hospital blood and urine were sent to NMS Labs for NBOMe and psilocin confirmation. The blood was positive for 25I-NBOMe, and the urine was positive for 25C-, 25H- and 25I-NBOMe, as well as, psilocin. Antemortem and postmortem blood were also sent to AIT Laboratories for NBOMe confirmation. The antemortem blood confirmed positive for 25I-NBOMe with a concentration of 0.76 ng/mL. The manner of death was ruled an accident as a result of combined 25I-NBOMe and psilocin intoxication.
Citations in the library
Cited by 25
- Neuropharmacology of N,N-dimethyltryptamine Brain Research Bulletin April 30, 2016
- Pharmacology and Toxicology of N-Benzylphenethylamine ("NBOMe") Hallucinogens. Current Topics in Behavioral Neurosciences 2017
- Integrating psychotherapy and psychopharmacology: psychedelic-assisted psychotherapy and other combined treatments Expert Review of Clinical Pharmacology June 1, 2020
- NBOMes–Highly Potent and Toxic Alternatives of LSD Frontiers in Neuroscience February 26, 2020
- Novel psychoactive substances: the pharmacology of stimulants and hallucinogens Expert Review of Clinical Pharmacology March 17, 2016
and 20 more in the library
Cites 5
- 25C-NBOMe: preliminary data on pharmacology, psychoactive effects, and toxicity of a new potent and dangerous hallucinogenic drug BioMed Research International 2014
- 2-(4-Iodo-2,5-dimethoxyphenyl)-N-[(2-methoxyphenyl)methyl]ethanamine (25I-NBOMe): clinical case with unique confirmatory testing. Journal of Medical Toxicology March 1, 2014
- Pathological findings in 2 cases of fatal 25I-NBOMe toxicity. American Journal of Forensic Medicine & Pathology March 1, 2014
- NBOMe — a very different kettle of fish … The Medical Journal of Australia September 1, 2013
- A case of 25I-NBOMe (25-I) intoxication: a new potent 5-HT2A agonist designer drug Clinical Toxicology March 1, 2013