25I-NBOMe related death in Australia: a case report.
Victoria B Kueppers, Clive T Cooke
Forensic Science International April 1, 2015 DOI: 10.1016/j.forsciint.2015.02.010 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Case study Case report Peer reviewed |
|---|---|
| Sample size | 1 |
| Population | One decedent from Australia |
| Keywords | 25i-nbome Fatality Nps |
| Key findings | A post mortem aortic blood concentration of 25I-NBOMe of approximately 28 μg/L was found, higher than previously reported in non-fatal and fatal cases. |
Abstract
We present a toxicologically confirmed 25I-NBOMe related death from Australia. 25I-NBOMe is a synthetic new psychoactive substance (NPS), which is a derivative of the 2C-X series of phenethylamines. NBOMe compounds have hallucinogenic and stimulant properties and are potent agonists of the human 5HT2A receptor. They have been associated with severe toxicity and fatalities. No case reports on deaths related to 25I-NBOMe toxicity from Australia have been published thus far. Very limited toxicological data is available in the current literature. The decedent in the presented case had a post mortem aortic non-preserved blood concentration of 25I-NBOMe of approximately 28 μg/L, a concentration that appears to be much higher than those previously reported in non-fatal cases of toxicity and analytically confirmed 25I-NBOMe related fatalities. The publication of new data is essential in improving knowledge and awareness amongst the forensic community regarding emerging psychoactive substances, such as the NBOMe compounds.
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- Designer drugs: mechanism of action and adverse effects Archives of Toxicology April 1, 2020
- Pharmacology and Toxicology of N-Benzylphenethylamine ("NBOMe") Hallucinogens. Current Topics in Behavioral Neurosciences 2017
- NBOMes–Highly Potent and Toxic Alternatives of LSD Frontiers in Neuroscience February 26, 2020
- DARK Classics in Chemical Neuroscience: NBOMes ACS Chemical Neuroscience October 28, 2019
- Hallucinogen-Like Action of the Novel Designer Drug 25I-NBOMe and Its Effect on Cortical Neurotransmitters in Rats Neurotoxicity Research April 15, 2019
and 28 more in the library
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- A case of 25I-NBOMe (25-I) intoxication: a new potent 5-HT2A agonist designer drug Clinical Toxicology March 1, 2013