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Mindfulness-based cognitive therapy: Further issues in current evidence and future research.

J. Mark G. Williams, Ian Russell, Daphne Russell

Journal of Consulting and Clinical Psychology June 1, 2008 DOI: 10.1037/0022-006x.76.3.524 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Reanalysis of randomized controlled trials Peer reviewed
Population Patients with three or more previous depressive episodes
Intervention Mindfulness-based cognitive therapy
Topics Anxiety Meditation
Keywords Mindfulness-based cognitive therapy Psychotherapist Beck depression inventory Clinical psychology Randomization Randomized controlled trial Cognition
Citations 165
Key findings For patients with three or more previous episodes, MBCT significantly reduced the risk of a further episode of depression and significantly decreased mean Beck Depression Inventory scores after treatment.

Abstract

The authors respond to the article by H. F. Coelho, P. H. Canter, and E. Ernst (2007), which reviewed the current status of mindfulness-based cognitive therapy (MBCT). First, they clarify the randomization procedures in the 2 main MBCT trials. Second, they report posttreatment and follow-up data to show that trial participants allocated to "treatment as usual" did not become worse. Third, they discuss which experimental designs are better for identification of the active component of treatment. Finally, they report reanalyses of the 2 main MBCT trials with multilevel modeling that corrected for intragroup correlations. These analyses reinforce the original findings: For patients with 3 or more previous episodes, MBCT significantly reduced the risk of a further episode of depression and significantly decreased mean scores on the Beck Depression Inventory (A. T. Beck, C. H. Ward, M. Mendelson, J. Mock, & J. Erbaugh, 1961) after treatment.

Comparable studies

Other randomized controlled trials on meditation, most cited first.

Study Year Design Participants
Alterations in Brain and Immune Function Produced by Mindfulness Meditation Healthy employees in a work environment 2003 Randomized controlled trial n = 41
Prevention of relapse/recurrence in major depression by mindfulness-based cognitive therapy. Recovered recurrently depressed patients 2000 Randomized controlled trial n = 145
Open hearts build lives: Positive emotions, induced through loving-kindness meditation, build consequential personal resources. Working adults 2008 Randomized controlled trial n = 139
Short-term meditation training improves attention and self-regulation Undergraduate Chinese students 2007 Randomized controlled trial n = 40
Mindfulness-Based Cognitive Therapy for Depression: Replication and Exploration of Differential Relapse Prevention Effects. Recovered recurrently depressed patients 2004 Randomized controlled trial n = 73

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