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Escitalopram for recurrent isolated sleep paralysis.

Jonathan P Hintze, Dominic Gault

Journal of Sleep Research December 1, 2020 DOI: 10.1111/jsr.13027 (opens in new tab) via PubMed

Summary

AI-generated from the abstract

Recurrent isolated sleep paralysis, which can be very disturbing and provoke anxiety, is usually treated with cognitive and behavioural therapies, but some patients may benefit from medication. With limited evidence available, there are no standardized pharmacologic recommendations. This report describes the first two cases where escitalopram, a selective serotonin reuptake inhibitor, successfully treated recurrent isolated sleep paralysis. Escitalopram generally improves subjective sleep quality, making it an appealing treatment option.

Study at a glance

Characteristics Case report Peer reviewed
Sample size 2
Population Patients with recurrent isolated sleep paralysis
Intervention Escitalopram
Keywords Antidepressant Hallucinations Hypnagogic Hypnopompic
Key finding Escitalopram successfully treated recurrent isolated sleep paralysis in two cases.

Abstract

Recurrent isolated sleep paralysis can be very disturbing and provoke anxiety. The majority of patients can be treated conservatively with cognitive and behavioural therapies. However, some patients may benefit from a pharmacologic intervention. With only scant available evidence, there are currently no standardized pharmacologic treatment recommendations for recurrent isolated sleep paralysis. We report the first two cases of escitalopram used to successfully treat recurrent isolated sleep paralysis. Escitalopram, the most selective of the selective serotonin reuptake inhibitors, generally improves subjective sleep quality, making it an appealing treatment option.

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