Influence of adjuvant mindfulness-based cognitive therapy (MBCT) on symptoms of post-traumatic stress disorder (PTSD) in veterans – results from a randomized control study
Mostafa Jasbi, Dena Sadeghi-Bahmani, G. Karami, Maryam Omidbeygi, M. Peyravi, Ailin Panahi, J. Mirzaee, Edith Holsboer-Trachsler, Serge Brand
Cognitive Behaviour Therapy June 12, 2018 DOI: 10.1080/16506073.2018.1445773 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Randomized controlled trial Peer reviewed |
|---|---|
| Sample size | 48 |
| Population | Male Iranian veterans of the Iran–Iraq war with PTSD |
| Interventions | Mindfulness-based cognitive therapy Citalopram |
| Dose | 30–50 mg/day |
| Duration | 8-week intervention |
| Topics | Meditation PTSD |
| Key findings | Adding MBCT to standard citalopram treatment significantly reduced symptoms of PTSD, depression, anxiety, and stress among veterans compared to standard treatment alone. |
Abstract
Abstract Even 30 or more years after the end of a war, veterans can suffer from post-traumatic stress disorder (PTSD). In the present study, we explored the influence on symptoms of PTSD among Iranian veterans of the Iran–Iraq war of mindfulness-based cognitive therapy (MBCT) as add-on to a standard treatment with citalopram. Forty-eight male veterans with PTSD (mean age: 52.97 years) took part in this eight-week intervention study. Standard treatment for all patients consisted of citalopram (30–50 mg/day at therapeutic dosages). Patients were randomly assigned either to the treatment or to the control condition. Treatment involved MBCT delivered in group sessions once a week. Patients in the control condition met at the hospital with the same frequency and duration for socio-therapeutic events. At baseline and at study completion, patients completed questionnaires covering symptoms of PTSD, depression, anxiety, and stress. At study completion after eight weeks, scores for PTSD (re-experiencing events, avoidance, negative mood and cognition, hyperarousal), depression, anxiety, and stress were lower, but more so in the intervention than the control group. Data suggest that, as adjuvant to standard SSRI medication, MBCT is an effective intervention to significantly reduce symptoms of PTSD, depression, anxiety, and stress among veterans.
Comparable studies
Other randomized controlled trials on PTSD, most cited first.
Citations in the library
Cited by 20
- Autobiographical Memory and Mindfulness: a Critical Review with a Systematic Search Mindfulness May 23, 2022
- Effectiveness of mindfulness based interventions in reducing depressive symptoms across mental disorders: A meta-analysis of randomized controlled trials. Psychiatry Research June 1, 2025
- The effect of mindfulness-based cognitive therapy on PTSD and depression symptoms in trauma-exposed black adults: Pilot randomized controlled trial results. Journal of Mood and Anxiety Disorders December 1, 2024
- Mindfulness-Based Interventions for Psychological Trauma and Posttraumatic Stress Disorder (PTSD) Current Treatment Options in Psychiatry July 30, 2025
- PSYCHOLOGICAL REHABILITATION OF MILITARY PERSONNEL THROUGH MINDFULNESS PRACTICES: CURRENT TENDENCIES AND EFFICIENCY Problems of engineer-pedagogical education December 30, 2025
and 15 more in the library
Cites 19
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- A PILOT STUDY OF GROUP MINDFULNESS-BASED COGNITIVE THERAPY (MBCT) FOR COMBAT VETERANS WITH POSTTRAUMATIC STRESS DISORDER (PTSD) Depression and Anxiety April 17, 2013
- A Randomized Controlled Trial of Mindfulness-Based Cognitive Therapy for Treatment-Resistant Depression Psychotherapy and Psychosomatics 2016
and 14 more in the library