Skip to content

Mindfulness-Based Stress Reduction and Mindfulness-Based Cognitive Therapy for Depression: A Systematic Review of Cognitive Outcomes

Morganne A. Kraines, Summer Peterson, Geoffrey Tremont, Courtney Beard, Judson A. Brewer, Lisa A Uebelacker

Mindfulness February 16, 2022 DOI: 10.1007/s12671-022-01841-7 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Systematic review Randomized Peer reviewed
Sample size 10
Population Individuals with at least mild depressive symptoms
Interventions Mindfulness-based stress reduction Mindfulness-based cognitive therapy
Topics Depression Meditation
Key findings Seven of ten studies showed at least one improvement in cognitive outcomes following MBSR or MBCT, while three studies showed no improvements.

Abstract

Summarize existing literature on cognitive outcomes of mindfulness-based stress reduction (MBSR) and mindfulness-based cognitive therapy (MBCT) for individuals with depression. Following PRISMA (2021) guidance, we conducted a systematic review. We searched databases for studies published from 2000 to 2020 which examined cognitive outcomes of MBSR and MBCT in individuals with at least mild depressive symptoms. The search results in 10 studies (11 articles) meeting inclusion criteria. We identified five single-arm trials and five randomized controlled trials. Results indicated that three studies did not show any improvements on cognitive outcomes, and seven studies showed at least one improvement in cognitive outcomes. Overall, the review highlighted several inconsistencies in the literature including inconsistent use of terminology, disparate samples, and inconsistent use of methodology. These inconsistencies may help to explain the mixed results of MBSR and MBCT on cognitive outcomes. Recommendations include a more streamlined approach to studying cognitive outcomes in depressed individuals in the context of MBSR and MBCT.

Comparable studies

Other systematic reviews and meta-analyses on depression, most cited first.

Study Year Design Participants
Ketamine and Other NMDA Antagonists: Early Clinical Trials and Possible Mechanisms in Depression Participants with major depression in placebo-controlled, double-blind, randomized... 2015 Systematic review and meta-analysis
Side-effects associated with ketamine use in depression: a systematic review. Patients with depression 2018 Systematic review
Comparative efficacy of racemic ketamine and esketamine for depression: a systematic review and meta-analysis Adults with unipolar or bipolar major depression 2020 Systematic review and meta-analysis n = 1,877
Single-dose infusion ketamine and non-ketamine N-methyl-D-aspartate receptor antagonists for unipolar and bipolar depression: a meta-analysis of efficacy, safety and time trajectories Patients with major depressive disorder or bipolar depression 2016 Systematic review and meta-analysis n = 588
Therapeutic effects of classic serotonergic psychedelics: A systematic review of modern‐era clinical studies Patients with cancer- or illness-related anxiety and depression, major depressive... 2020 Systematic review n = 188

Citations in the library

Cited by 7

and 2 more in the library

Cites 14

and 9 more in the library

Explore topics