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Defining and measuring meditation-related adverse effects in mindfulness-based programs

Willoughby B. Britton, Jared R. Lindahl, David J. C. Cooper, Nicholas K. Canby, Roman Palitsky

Clinical Psychological Science May 18, 2021 DOI: 10.1177/2167702621996340 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Observational cohort Peer reviewed
Sample size 96
Population Adults participating in an 8-week mindfulness-based cognitive therapy program
Intervention Mindfulness-based cognitive therapy
Duration 8-week program
Topics Meditation
Key findings Eighty-three percent of participants reported at least one meditation-related side effect, with lasting bad effects occurring in 6% to 14% and associated with dysregulated arousal.

Abstract

Research on the adverse effects of mindfulness-based programs (MBPs) has been sparse and hindered by methodological imprecision. The 44-item Meditation Experiences Interview (MedEx-I) was used by an independent assessor to measure meditation-related side effects (MRSEs) following three variants of an 8-week program of mindfulness-based cognitive therapy (n = 96). Each item was queried for occurrence, causal link to mindfulness meditation practice, duration, valence, and impact on functioning. Eighty-three percent of the MBP sample reported at least one MRSE. Meditation-related adverse effects with negative valences or negative impacts on functioning occurred in 58% and 37% of the sample, respectively. Lasting bad effects occurred in 6% to 14% of the sample and were associated with signs of dysregulated arousal (hyperarousal and dissociation). Meditation practice in MBPs is associated with transient distress and negative impacts at similar rates to other psychological treatments.

Comparable studies

Other observational and cohort studies on meditation, most cited first.

Study Year Design Participants
Using Self-Report Assessment Methods to Explore Facets of Mindfulness Undergraduate students 2006 Observational cohort
Effectiveness of a meditation-based stress reduction program in the treatment of anxiety disorders Patients with generalized anxiety disorder or panic disorder with or without agoraphobia 1992 Observational cohort n = 22
Meditation experience is associated with increased cortical thickness Participants with extensive Insight meditation experience and matched controls 2005 Observational cohort n = 20
Meditation experience is associated with differences in default mode network activity and connectivity Experienced meditators and matched meditation-naive controls 2011 Observational cohort
Long-term meditators self-induce high-amplitude gamma synchrony during mental practice Long-term Buddhist practitioners and controls 2004 Observational cohort

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