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Importance of Integrating Spiritual, Existential, Religious, and Theological Components in Psychedelic-Assisted Therapies.

Roman Palitsky, Deanna M Kaplan, Caroline Peacock, Ali John Zarrabi, Jessica L Maples-Keller, George H. Grant, Boadie W Dunlop, Charles L. Raison

JAMA Psychiatry July 1, 2023 DOI: 10.1001/jamapsychiatry.2023.1554 (opens in new tab)

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AI-extracted from the abstract
Characteristics Review Peer reviewed
Topics Psychedelic-assisted therapy
Citations 86
Key findings Spiritual, existential, religious, and theological components should be systematically integrated into psychedelic-assisted therapy to ensure culturally competent, evidence-based treatment.

Abstract

Mounting evidence supports the role of spiritual, existential, religious, and theological components in mediating psychedelic-assisted therapy, yet integration of these elements into the clinical setting is lagging. Although psychedelic-assisted therapy commonly produces spiritually, existentially, religiously, or theologically relevant experiences for patients, these have not been systematically integrated into the psychotherapies that accompany therapeutic uses of psychedelics. As a key feature and potential mediator of therapeutic effects, evidence-based psychedelic-assisted therapies should include these topics in the treatment model. Research across multiple diagnostic targets and treatment contexts suggests that spiritually integrated psychotherapies are effective, feasible, and produce add-on benefits in spiritually, existentially, religiously, and theologically relevant outcomes, which are particularly germane to psychedelics. Established standards in spiritually integrated psychotherapy may be fruitfully applied to psychedelic-assisted therapy. Objectives for spiritually, existentially, religiously, and theologically integrated psychedelic-assisted therapy based on these standards and informed by considerations specific to psychedelics are recommended. Spiritual, existential, religious, and theological topics' integration in psychedelic-assisted therapy is needed to ensure culturally competent, evidence-based treatment aligned with the highest standards of clinical care. Neglecting to address these topics can detract from cultural competence, contribute to risks for patients, and potentially undermine treatment success.

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