Psychedelics and psychological strengths
Trey Brasher, David Rosen, Marcello Spinella
International Journal of Wellbeing February 28, 2023 DOI: 10.5502/ijw.v13i1.2325 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Cross-sectional survey Randomized Peer reviewed |
|---|---|
| Sample size | 3,157 |
| Population | Adults recruited via online survey |
| Keywords | Psychedelics Mental health Psychological resilience Well-being Personal growth |
| Citations | 9 |
| Key findings | Classical psychedelic users show greater psychological strengths and well-being, and lower distress, than non-users, with the effect fully mediated by self-transcendence. |
Abstract
Classical psychedelics appear efficacious in improving psychological well-being in randomized clinical trials, but their effects in the population at large are relatively unknown. In the present paper, which includes three studies conducted by online survey with a collective 3,157 participants, classical psychedelic users showed greater psychological strengths and well-being, and lower levels of distress, after controlling for demographic variables, respondents’ beliefs about the potential benefits of psychedelics, and their use of other psychoactive drugs. These benefits contrast with patterns for cannabis and alcohol users, both of whom showed comparatively maladaptive profiles. Reported relationships between psychedelic use and the combined index of psychological strengths was fully mediated by self-transcendence. We show an effect of motivation for psychedelic use, where those who reported a ‘growth’ motivation showed the most robustly adaptive psychological profile. Psychedelic users reported more lifetime meditation experience, and within psychedelic users, greater frequency of use correlated with greater hours of lifetime seated meditation practice. Meditation experience did not account for the differences in strengths, well-being, and distress. In these studies, psychedelic users showed an adaptive psychological pattern on a wider array of strengths than previously studied, which were not attributable to several salient covariates. While causality cannot be inferred from this study, findings align with and advance past research which provides evidence for the potential benefits associated with psychedelics
Citations in the library
Cited by 6
- From Policy to Perception: Do Public Views on UK Drug Policy Shape Attitudes Toward Psychedelics? Journal of Psychoactive Drugs September 11, 2025
- Psychedelic Use and Behavioral Addictions. Journal of Psychoactive Drugs March 15, 2025
- Do undergraduates’ views of psychedelics relate to the context for psychedelic use? Drug Science, Policy and Law March 1, 2025
- Psychedelic Use and Mystical-Type Experiences are Associated With Greater Self-Compassion, Compassionate Love, and Life Satisfaction Journal of Humanistic Psychology April 28, 2026
- Psychoactive Substances in Daoist Practice: A Cultural and Historical Perspective Religions April 2, 2026
and 1 more in the library
Cites 109
- The benefits of being present: Mindfulness and its role in psychological well-being. Journal of Personality and Social Psychology 2003
- Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial Journal of Psychopharmacology November 30, 2016
- Rapid and sustained symptom reduction following psilocybin treatment for anxiety and depression in patients with life-threatening cancer: a randomized controlled trial Journal of Psychopharmacology November 30, 2016
- Psilocybin can occasion mystical-type experiences having substantial and sustained personal meaning and spiritual significance Psychopharmacology July 7, 2006
- Meditation experience is associated with differences in default mode network activity and connectivity Proceedings of the National Academy of Sciences November 23, 2011
and 104 more in the library