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Psychedelic Use and Mystical-Type Experiences are Associated With Greater Self-Compassion, Compassionate Love, and Life Satisfaction

Austin J. Mallard, Matthew Broussard, Richard J. Zeifman, Derek Espinoza, Scott Cloutier, Stephen Ross, Michael P. Bogenschutz, Broc A. Pagni

Journal of Humanistic Psychology April 28, 2026 DOI: 10.1177/00221678261442571 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Cross-sectional study Peer reviewed
Sample size 984
Population Adults, including psychedelic-naive individuals, former users, and current users
Topics Mystical experience
Keywords Life satisfaction Interpersonal communication Compassionate use Empathy Interpersonal relationship Clinical psychology Psychotherapist Depression economics
Key findings Current and former psychedelic users reported significantly greater compassionate love, self-compassion, life satisfaction, and lifetime mystical-type experiences than psychedelic-naive individuals.

Abstract

Emerging evidence suggests psychedelic-assisted therapies ameliorate symptoms of psychopathology. However, less is known about how psychedelics influence positive psychological functioning (e.g., compassionate love, self-compassion, and life satisfaction). These constructs may be relevant in understanding how psychedelics exert their therapeutic effects, as they are central to both intra- and interpersonal well-being, and may function as protective factors against psychopathology. In a cross-sectional sample ( N = 984), we compared psychedelic-naive individuals ( n = 169) to former ( n = 178) and current ( n = 637) psychedelic users on compassionate love, self-compassion, life satisfaction, and lifetime mystical-type experiences (MTEs). After controlling for confounding variables, current and former users reported significantly greater compassionate love, self-compassion, life satisfaction, and lifetime MTEs than psychedelic-naive individuals. Relative to former users, current psychedelic users reported significantly greater self-compassion, life satisfaction, and lifetime MTEs, but not compassionate love. Across all groups, lifetime MTEs were positively associated with positive psychological functioning, suggesting that relationships between MTEs and psychological functioning may not be restricted to psychedelic use. Although limited by self-reporting biases, a cross-sectional design, and a homogenous sample, our findings suggest psychedelic use and MTEs are associated with positive psychological functioning, warranting further examination of these psychological constructs in clinical trials.