Cannabis-induced psychosis: a cross-sectional comparison with acute schizophrenia.
L A Núñez, M Gurpegui
Acta Psychiatrica Scandinavica March 1, 2002 DOI: 10.1034/j.1600-0447.2002.1o079.x (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Observational cohort Cross-sectional Peer reviewed |
|---|---|
| Sample size | 61 |
| Population | Patients with cannabis-induced psychosis or acute schizophrenia, confirmed by repeated urine screens for cannabis consumption |
| Duration | At least 1 week but not more than 1 month of abstinence for cannabis-induced psychosis group |
| Topics | Cannabis |
| Key findings | Cannabis-induced psychosis and acute schizophrenia have distinct demographic, premorbid, and clinical features, supporting cannabis-induced psychosis as a separate clinical entity. |
Abstract
The existence of cannabis-induced psychosis (CP) remains controversial, partly because of methodological problems. We hypothesize that acute schizophrenia (AS) and CP can have distinct demographic, premorbid and clinical features. We compared 26 patients with CP to 35 with AS, after their cannabis-consumption status was confirmed by repeated urine screens. Patients with CP were assessed after at least 1 week but not more than 1 month of abstinence. Symptoms were evaluated with the Present State Examination (PSE). In group CP, male gender, expansive mood and ideation, derealization/depersonalization, visual hallucinations, and disturbances of sensorium were more frequent than in group AS. Premorbid schizoid personality traits were more frequently associated to AS and antisocial personality traits to CP. The continuous heavy use of cannabis can induce a psychotic disorder distinct from AS. These two clinical entities share some features but they differ in others.
Comparable studies
Other observational and cohort studies on cannabis, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| High-potency cannabis and the risk of psychosis People with first episode of psychosis and healthy controls from the local population | 2009 | Case-control study | n = 454 |
| Ayahuasca-Assisted Therapy for Addiction: Results from a Preliminary Observational Study in Canada Rural aboriginal population | 2013 | Observational study | |
| Impaired cognitive performance in drug free users of recreational ecstasy (MDMA) Otherwise healthy young people | 2000 | Observational | |
| Continued cannabis use and risk of incidence and persistence of psychotic symptoms: 10 year follow-up cohort study Individuals from the general population in Germany aged 14-24 at baseline | 2011 | Observational cohort | n = 1,923 |
| Cannabis-induced psychosis and subsequent schizophrenia-spectrum disorders: follow-up study of 535 incident cases Patients treated for cannabis-induced psychotic symptoms in Denmark between 1994 and... | 2005 | Observational cohort | n = 535 |
Citations in the library
Cited by 26
- Cannabis use and psychotic disorders: an update Drug and Alcohol Review November 30, 2004
- Familial Predisposition for Psychiatric Disorder Archives of General Psychiatry November 3, 2008
- Visual scan paths in first-episode schizophrenia and cannabis-induced psychosis Journal of Psychiatry and Neuroscience July 1, 2007
- Psicosis inducida por cannabis: características clínicas y su diferenciación con la esquizofrenia con y sin consumo de cannabis asociado Adicciones July 14, 2020
- Revisión sobre el consumo de cannabis como factor de riesgo de la esquizofrenia Adicciones June 1, 2007
and 21 more in the library
Cites 19
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- Drug Induced Psychosis The British Journal of Psychiatry February 1, 1996
- Marihuanann Psychosis JAMA October 13, 1969
- Elevated endogenous cannabinoids in schizophrenia. Neuroreport June 3, 1999
- Cannabis psychosis and acute schizophrenia. a case-control study from India. European Addiction Research June 1, 1999
and 14 more in the library