Cannabis and acute psychosis.
Philip Mcguire, P Jones, I Harvey, P Bebbington, B Toone, S Lewis, Robin Murray
Schizophrenia Research September 1, 1994 DOI: 10.1016/0920-9964(94)90097-3 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Observational cohort Peer reviewed |
|---|---|
| Sample size | 69 |
| Population | Psychotic patients |
| Topics | Cannabis |
| Key findings | Psychosis in cannabis-positive patients does not differ in psychopathology, diagnosis, or onset from psychosis in drug-free controls, providing little evidence for a distinct 'cannabis psychosis' entity. |
Abstract
The Present State Examination was used to assess the psychopathology of 23 psychotic patients who were cannabis positive on urinary screening, and 46 matched drug-free controls. Cases and controls were indistinguishable in terms of psychopathology, DSMIII diagnoses, onset of recent illness, the proportion of first admissions, ethnicity, and socio-economic class, differing only in their histories of substance use. These data suggest that psychosis which develops or recurs in the context of cannabis use does not have a characteristic psychopathology or mode of onset, and is not restricted to a particular ethnic or socio-demographic group. There is thus little evidence to support the validity of 'cannabis psychosis' as a diagnostic entity.
Comparable studies
Other observational and cohort studies on cannabis, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| High-potency cannabis and the risk of psychosis People with first episode of psychosis and healthy controls from the local population | 2009 | Case-control study | n = 454 |
| Ayahuasca-Assisted Therapy for Addiction: Results from a Preliminary Observational Study in Canada Rural aboriginal population | 2013 | Observational study | |
| Impaired cognitive performance in drug free users of recreational ecstasy (MDMA) Otherwise healthy young people | 2000 | Observational | |
| Continued cannabis use and risk of incidence and persistence of psychotic symptoms: 10 year follow-up cohort study Individuals from the general population in Germany aged 14-24 at baseline | 2011 | Observational cohort | n = 1,923 |
| Cannabis-induced psychosis and subsequent schizophrenia-spectrum disorders: follow-up study of 535 incident cases Patients treated for cannabis-induced psychotic symptoms in Denmark between 1994 and... | 2005 | Observational cohort | n = 535 |
Citations in the library
Cited by 22
- Psychiatric effects of cannabis The British Journal of Psychiatry February 1, 2001
- Diversity of Psychopathology Associated with use of 3,4-Methylenedioxymethamphetamine (‘Ecstasy’) The British Journal of Psychiatry September 1, 1994
- Cannabis use and psychotic disorders: an update Drug and Alcohol Review November 30, 2004
- New Perspectives in the Studies on Endocannabinoid and Cannabis: Cannabinoid Receptors and Schizophrenia Journal of Pharmacological Sciences 2004
- Potential antipsychotic properties of central cannabinoid (CB1) receptor antagonists The World Journal of Biological Psychiatry March 1, 2010
and 17 more in the library
Cites 8
- Psychotic Reactions Following Cannabis Use in East Indians Archives of General Psychiatry 1974
- Diversity of Psychopathology Associated with use of 3,4-Methylenedioxymethamphetamine (‘Ecstasy’) The British Journal of Psychiatry September 1, 1994
- LSD Psychosis or LSD-Induced Schizophrenia? Archives of General Psychiatry August 1, 1983
- Forty-Six Cases of Psychosis in Cannabis Abusers Gunila Bernhardson International Journal of the Addictions 1972
- Community-initiated research: a study of psychiatrists' conceptualisations of ‘cannabis psychosis’ Psychiatric Bulletin November 1, 1988
and 3 more in the library