Effects of infused tryptamine in man
Psychopharmacologia September 1, 1970 DOI: 10.1007/bf00412669 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Experimental study Peer reviewed |
|---|---|
| Population | Human subjects |
| Intervention | Tryptamine |
| Topics | LSD |
| Keywords | Tryptamine Subjective effects Drug-induced psychosis |
| Key findings | Intravenous tryptamine produces physiological and subjective effects similar to LSD-like hallucinogens, consistent with the hypothesis that these hallucinogens interact with tryptamine receptors. |
Abstract
Tryptamine, infused intravenously in man, facilitates the patellar reflex, dilates pupils and elevates blood pressure. It also causes changes in vision and hearing, as well as nausea, vomiting, dizziness, sweating and heaviness of body. These changes are similar to those produced by LSD-like hallucinogens and are consistent with the hypothesis that LSD-like hallucinogens interact with tryptamine receptors as one mode of action.