Disorders due to Substance Use: Hallucinogens and MDMA-Related Substances
Sandeep M. Nayak, Matthew W. Johnson
Tasman’s Psychiatry 2023 DOI: 10.1007/978-3-030-42825-9_94-1 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Review Peer reviewed |
|---|---|
| Topics | MDMA Addiction |
| Keywords | Psychedelic Hallucinogen Disorders Harm Risks Psychosis |
| Key findings | Classic psychedelics and MDMA are associated with a range of adverse effects including acute toxicity, abuse potential, persistent perceptual effects, psychosis, and neurotoxicity. |
Abstract
Hallucinogens are a broad category of substances encompassing drugs with diverse pharmacological, phenomenological, and adverse effects. In this chapter, the focus is on disorders caused by and exacerbated by two classes of hallucinogens. These are classic psychedelics (drugs including LSD and psilocybin that exert subjective effects principally by 5HT_2A agonism) and the substituted amphetamine 3,4-methylenedioxymethamphetamine (MDMA). In this chapter, the evidence regarding disorders and other adverse effects attributable to these drugs, including acute toxicity, abuse potential, persistent perceptual effects (Hallucinogen Persisting Perception Disorder), psychosis, neurotoxicity, and more, are explored.