The 3D-ASCr scale: A revalidation of the core dimensions of the Altered States of Consciousness Rating Scale 5D(11)-ASC for psychedelic research
Kurt Stocker, Matthias Hartmann, Schmid, Yasmin, Severin B Vogt, Anna M Becker, Laura Ley, Isabelle Straumann, Denis Arikci, Aaron Klaiber, Livio Erne, Patrick Vizeli, Friederike Holze, Matthias E. Liechti
Repository for Publications and Research Data January 1, 2025 DOI: 10.3929/ethz-c-000791180 (opens in new tab) via OpenAlex
Summary
AI-generated from the abstractThe Altered States of Consciousness Scale (ASC), commonly used in psychedelic research, has two incompatible scoring systems: a three-dimensional model (3D-ASC) and an eleven-subscale model (11-ASC). Analyzing data from 901 questionnaires across 16 psychedelic studies, researchers found that ten of the eleven subscales could be reorganized into three higher-order dimensions—Positive, Distressing, and Perceptual effects—that closely mirror the original three dimensions but with improved statistical fit. This revised version, called the 3D-ASCr, retains the Anxiety subscale separately due to floor effects. The 3D-ASCr is recommended for use with classic serotonergic psychedelics in clinical practice and research.
Study at a glance
| Characteristics | Exploratory and confirmatory factor analysis Randomized Placebo-controlled Peer reviewed |
|---|---|
| Sample size | 398 |
| Population | Healthy participants across 16 randomized, mostly placebo-controlled psychedelic studies |
| Interventions | lysergic acid diethylamide psilocybin mescaline N N-dimethyltryptamine |
| Topics | Anxiety |
| Keywords | Revalidation Confirmatory factor analysis Rating scale Scale ratio |
| Key finding | Ten of the 11 ASC subscales formed three higher-order dimensions (Positive, Distressing, and Perceptual effects) that mirror the original 3D-ASC but with improved model fit. |
Abstract
Background: The Altered States of Consciousness Scale (3/5D-ASC or 11-ASC) is widely used to assess non-ordinary states of consciousness, particularly for psychedelic research. However, its original dimensional model (3D-ASC within 5D-ASC) and later 11-subscale structure (11-ASC) have a hierarchically incompatible higher/lower-order structure. Although the 11-ASC offers superior model fit, the 3D-ASC remains widely used for summarizing broader experiential domains. Aims: We wanted to provide an updated, psychometrically revalidated version of the ASC. We tested whether the 42-item 11-ASC could be integrated into a coherent three-dimensional framework. We further hypothesized that this revised model would outperform the original 66-item 3D-ASC while preserving its conceptual clarity. Methods: Data from 901 5D-ASC questionnaires from 398 healthy participants across 16 randomized, mostly placebo-controlled psychedelic (lysergic acid diethylamide, psilocybin, mescaline, and N,N-dimethyltryptamine) studies were split for exploratory and confirmatory factor analysis. We compared the 3D-ASC and 11-ASC in terms of reliability and model fit, and tested whether the 11-ASC could be summarized within a three-dimensional model. Results: Ten of the 11 subscales formed three higher-order dimensions—Positive (PosE), Distressing (DisE), and Perceptual (PerE) effects—mirroring the 3D-ASC but with improved fit. We propose this as the 3D-ASCr scale. The Anxiety subscale could not be integrated due to consistent floor effects (low anxiety in the sample), but given its clinical relevance, it is retained within 3D-ASCr (as part of DisE or a standalone subscale). Conclusion: The 3D-ASCr is an updated version of the ASC and is recommended for use with classic serotonergic psychedelics in both clinical practice and research.