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Does Psychological Flexibility Correlate with Mystical Experiences: A Machine Learning Approach Including State of Surrender, Near-Death Experiences, and Psilocybin Consumption.

Dylan Briggs, Thomas B Sease, Ruthie Menou, David R Perkins

Behavioral sciences (Basel, Switzerland) April 30, 2026 DOI: 10.3390/bs16050686 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Observational study Peer reviewed
Sample size 150
Population Adults recruited online
Topics Mystical experience Near-death experience Psilocybin
Keywords Mystical experiences Near death experiences Psychedelic use Psychological flexibility State of surrender
Key findings State of Surrender, experiential acceptance, cognitive defusion, and present-moment awareness were the most robust predictors of mystical experiences.

Abstract

Mystical experiences are characterized by a profound sense of interconnectedness and transcendence of ordinary reality. These experiences can facilitate feelings of connectedness with oneself and others and have been documented as leading to significant positive changes in thoughts, emotions, and behavior. The purpose of the present study was to evaluate the extent to which the four mindfulness facets of psychological flexibility (i.e., experiential acceptance, present-moment awareness, cognitive defusion, and self-as-context) were associated with self-reported mystical experiences while controlling for established covariates. Using a sample of 150 individuals recruited online, a regularized regression with an elastic net-a computationally efficient machine learning algorithm-was used to model the relationships among mystical experiences, State of Surrender, frequency of psychedelic use, near-death experiences, and facets of psychological flexibility. State of Surrender, experiential acceptance, cognitive defusion, and present-moment awareness emerged as the most robust predictors of mystical experiences. Collectively, these findings underscore the role of psychological processes, including surrender-related processes and facets of psychological flexibility, in predicting mystical experiences.