Lysergic Acid Diethylamide: Radioimmunoassay
Alison Taunton-Rigby, S. Sher, Paul R. Kelley
Science July 13, 1973 DOI: 10.1126/science.181.4095.165 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Laboratory method development Peer reviewed |
|---|---|
| Topics | LSD Serotonin |
| Keywords | Radioimmunoassay Conjugate Antibody Human serum albumin Chromatography Biochemistry Immunology Receptor |
| Citations | 50 |
| Key points | A radioimmunoassay using antibodies raised against an LSD-human serum albumin conjugate can detect picogram amounts of LSD in human urine. |
Abstract
A radioimmnunoassay for d-lysergic acid diethylamide (LSD) is described. Antibodies to LSD were obtained by immunizing rabbits with a conjugate of LSD and human serum albumin. The specificity of the antibody was shown by competitive binding studies. The method has been used to detect the presence of LSD in human urines. Picogram amounts can be measured by this assay.