The impact of drug control on wider research: Psychedelic mushroom exploration
Sam Lasham, Rhys Ponton
Drug Science, Policy and Law 2026 DOI: 10.1177/20503245251412697 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Short paper Peer reviewed |
|---|---|
| Topics | Psilocybin |
| Keywords | Drug control Clinical research Control management Compassionate use Alternative medicine Engineering ethics Pharmacology Law Drug approval |
| Citations | 1 |
| Key points | Drug control laws, particularly New Zealand's Misuse of Drugs Act 1975, impede not only clinical research on psychedelics but also non-clinical research such as that on mushroom-forming fungi. |
Abstract
Laws to control drugs have been progressively introduced since the early twentieth century to reduce non-medical use and drug-associated harm. Restrictions on what are now deemed ‘controlled drugs’ and, in New Zealand, ‘prohibited plants’ unjustly impact both medical care and research. The impact on research has frequently been cited in reference to the use of drugs in clinical research, such as the use of 3,4-methylenedioxymethamphetamine (MDMA) and psychedelic drugs (lysergic acid diethylamide (LSD), psilocybin, and n,n-dimethyltryptamine (DMT)). The complexities and legal requirements involved in their use, or simply the inability to legally access these drugs at all, has limited research for decades. While restrictions on research into the clinical applications of these drugs have been commonly reported, legal restrictions also inhibit or severely restrict other research areas. This short paper describes the impedance that drug law can have on research in non-clinical areas, with a discussion of the impact of the Misuse of Drugs Act 1975 on research of mushroom-forming fungi in New Zealand.
Citations in the library
Cites 6
- From Egoism to Ecoism: Psychedelics Increase Nature Relatedness in a State-Mediated and Context-Dependent Manner. International Journal of Environmental Research and Public Health December 16, 2019
- Diversity, biology, and history of psilocybin-containing fungi: Suggestions for research and technological development. Fungal biology April 1, 2022
- Active Metabolite of Aeruginascin (4-Hydroxy-N,N,N-trimethyltryptamine): Synthesis, Structure, and Serotonergic Binding Affinity ACS Omega July 2, 2020
- Pharmacological and behavioural effects of tryptamines present in psilocybin‐containing mushrooms British Journal of Pharmacology June 2, 2024
- Development of an E. coli-based norbaeocystin production platform and evaluation of behavioral effects in rats Metabolic Engineering Communications March 11, 2022
and 1 more in the library