The Toxicity of Chlorpromazine and Mescaline on Mouse Cerebellum and Fibroblast Cells in Culture*
I. F. Roubein, M. Samuelly, W Keup
Acta Pharmacologica et Toxicologica November 1, 1973 DOI: 10.1111/j.1600-0773.1973.tb01534.x (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | In vitro study Peer reviewed |
|---|---|
| Population | Mouse cerebellum and fibroblast cells |
| Interventions | Chlorpromazine Mescaline |
| Topics | Mescaline |
| Keywords | Chlorpromazine Cerebellum Fibroblast Toxicity In vitro Pharmacology |
| Citations | 4 |
| Key points | Chlorpromazine is more toxic than mescaline to both cell types, and fibroblasts are more sensitive than cerebellum cells to both drugs. |
Abstract
Abstract: The toxicity of chlorpromazine (CPZ) and mescaline (MCL) to mouse cerebellum and fibroblast cells was studied in vitro . CPZ proved to be more toxic than MCL to both tissues. Fibroblast celles are more sensitive than the cerebellum to both CPZ and MCL.
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| Lysergic Acid Diethylamide- and Mescaline-Induced Attenuation of the Effect of Punishment in the Rat Rats | 1976 | Experimental study | |
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