Effect of 5, 6-dihydroxytryptamine on the head twitches induced by 5-HTP, 5-HT, mescaline and fludiazepam in mice
Mitsutaka Nakamura, Hideaki Fukushima
Journal of Pharmacy and Pharmacology September 1, 1978 DOI: 10.1111/j.2042-7158.1978.tb13156.x (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Experimental study Peer reviewed |
|---|---|
| Population | Mice |
| Interventions | 5 6-dihydroxytryptamine 5-HTP 5-HT mescaline fludiazepam |
| Topics | Mescaline Serotonin |
| Keywords | Pharmacy Library science Management |
| Citations | 25 |
| Key findings | 5,6-dihydroxytryptamine suppressed head twitches induced by 5-HTP, 5-HT, mescaline, and fludiazepam in mice, with varying degrees of inhibition. |
Abstract
Journal Article Effect of 5, 6-dihydroxytryptamine on the head twitches induced by 5-HTP, 5-HT, mescaline and fludiazepam in mice Get access Mitsutaka Nakamura, Mitsutaka Nakamura Research and Development Centre, Pharmaceuticals Division, Sumitomo Chemical Co. Ltd., 4-2-1, Takatusukasa, Takarazuka, Hyogo, 665, Japan Correspondence: Research and Development Centre, Pharmaceuticals Division, Sumitomo Chemical Co. Ltd., 4-2-1, Takatusukasa, Takarazuka, Hyogo, 665, Japan Search for other works by this author on: Oxford Academic Google Scholar Hideaki Fukushima Hideaki Fukushima Research and Development Centre, Pharmaceuticals Division, Sumitomo Chemical Co. Ltd., 4-2-1, Takatusukasa, Takarazuka, Hyogo, 665, Japan Search for other works by this author on: Oxford Academic Google Scholar Journal of Pharmacy and Pharmacology, Volume 30, Issue 1, September 1978, Pages 56–58, https://doi.org/10.1111/j.2042-7158.1978.tb13156.x Published: 12 April 2011 Article history Received: 01 August 1977 Published: 12 April 2011
Comparable studies
Other preclinical and animal studies on mescaline, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Correlation between the potency of hallucinogens in the mouse head-twitch response assay and their behavioral and subjective effects in other species. C57BL/6J mice | 2020 | Experimental study with dose-response experiments | |
| Brain mechanisms of hallucinogens and entactogens Humans and rats | 2001 | Review | |
| Effects of hallucinogenic agents mescaline and phencyclidine on zebrafish behavior and physiology Zebrafish (Danio rerio) | 2012 | Experimental study | |
| Lysergic Acid Diethylamide- and Mescaline-Induced Attenuation of the Effect of Punishment in the Rat Rats | 1976 | Experimental study | |
| Dihydrobenzofuran Analogues of Hallucinogens. 3. Models of 4-Substituted (2,5-Dimethoxyphenyl)alkylamine Derivatives with Rigidified Methoxy Groups Rats (trained to discriminate saline from LSD tartrate) and rat cortical and... | 1996 | In vivo drug discrimination assay and in vitro radioligand binding assay |
Citations in the library
Cited by 4
- Mescaline‐induced head‐twitches in the rat: An in vivo method to evaluate serotonin S2 antagonists Drug Development Research 1983
- The effect of benzodiazepines on the 5-HT agonist-induced head-twitch response in mice. European Journal of Pharmacology July 7, 1988
- Dissociation of head twitches and tremors during the study of interactions with 5-hydroxytryptophan in mice. Journal of pharmacological methods June 1, 1985
- Stimulation of human prolactin secretion by mescaline Psychopharmacology September 1, 1979