The History of MDMA as an Underground Drug in the United States, 1960–1979
Torsten Passie, Udo Benzenhöfer
Journal of Psychoactive Drugs March 3, 2016 DOI: 10.1080/02791072.2015.1128580 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Historical analysis Peer reviewed |
|---|---|
| Topics | MDMA |
| Keywords | Recreational drug Recreational use Mephedrone Hallucinogen Designer drug |
| Citations | 56 |
| Key points | Reconstructs the early history of MDMA as a recreational drug in the U.S. from 1960 to 1979, showing it was first synthesized by underground chemists as a legal alternative to MDA and first detected on the street in Chicago in 1970. |
Abstract
MDMA (3,4-methylenedioxy-methylamphetamine, a.k.a. "ecstasy") was first synthesized in 1912 and resynthesized more than once for pharmaceutical reasons before it became a popular recreational drug. Partially based on previously overlooked U.S. government documentation, this article reconstructs the early history of MDMA as a recreational drug in the U.S. from 1960 to 1979. According to the literature, MDMA was introduced as a street drug at the end of the 1960s. The first forensic detection of MDMA "on the street" was reported in 1970 in Chicago. It appears that MDMA was first synthesized by underground chemists in search of "legal alternatives" for the closely related and highly sought-after drug MDA, which was scheduled under the Controlled Substances Act (CSA) in 1970. Until 1974, nearly all MDMA street samples seized came from the U.S. Midwest, the first "hot region" of MDMA use. In Canada, MDMA was first detected in 1974 and scheduled in 1976. From 1975 to 1979, MDMA was found in street samples in more than 10 U.S. states, the West Coast becoming the major "hot region" of MDMA use. Recreational use of MDMA spread across the U.S. in the early 1980s, and in 1985 it was scheduled under the CSA.
Comparable studies
Other theoretical and historical papers on MDMA, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Differences Between the Mechanism of Action of MDMA, MBDB, and the Classic Hallucinogens. Identification of a New Therapeutic Class: Entactogens | 1986 | Theoretical or philosophical paper | |
| The Background and Chemistry of MDMA | 1986 | Historical analysis | |
| The origin of MDMA (ecstasy) revisited: the true story reconstructed from the original documents* Original documents in Merck's historical archive in Darmstadt, Germany, years 1900–1960 | 2006 | Historical analysis | |
| Distinct neural mechanisms for the prosocial and rewarding properties of MDMA | 2019 | Theoretical or philosophical paper | |
| How could MDMA (ecstasy) help anxiety disorders? A neurobiological rationale | 2009 | Theoretical or philosophical paper |
Citations in the library
Cited by 41
- The early use of MDMA (‘Ecstasy’) in psychotherapy (1977–1985) Drug Science, Policy and Law 2018
- Combining Cognitive-Behavioral Conjoint Therapy for PTSD with 3,4-Methylenedioxymethamphetamine (MDMA): A Case Example. Journal of Psychoactive Drugs 2019
- Classic and non‐classic psychedelics for substance use disorder: A review of their historic, past and current research Addiction Neuroscience June 22, 2022
- MDMA and MDMA-Assisted Therapy. American Journal of Psychiatry 2025
- Deaths related to MDMA (ecstasy/molly): Prevalence, root causes, and harm reduction interventions Journal of Substance Use February 20, 2018
and 36 more in the library
Cites 9
- Differences Between the Mechanism of Action of MDMA, MBDB, and the Classic Hallucinogens. Identification of a New Therapeutic Class: Entactogens Journal of Psychoactive Drugs October 1, 1986
- The Background and Chemistry of MDMA Journal of Psychoactive Drugs October 1, 1986
- MDMA: Nonmedical Use and Intoxication Journal of Psychoactive Drugs October 1, 1986
- An Exploration of the History and Controversies Surrounding MDMA and MDA Journal of Psychoactive Drugs September 1, 2001
- Methylenedioxyamphetamine (MDA)–Subjective Effects Journal of Psychedelic Drugs 1974
and 4 more in the library