Hyponatraemic states following 3,4-methylenedioxymethamphetamine (MDMA, 'ecstasy') ingestion
The Quarterly journal of medicine July 1, 2002 DOI: 10.1093/qjmed/95.7.431 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Review Peer reviewed |
|---|---|
| Topics | MDMA |
| Keywords | Ingestion Antidiuretic Hyponatremia Vomiting Anesthesia Hormone |
| Citations | 122 |
| Key findings | MDMA can cause life-threatening hyponatraemic encephalopathy when accompanied by excessive fluid ingestion, due to inappropriate secretion of antidiuretic hormone. |
Abstract
MDMA can cause life-threatening hyponatraemic encephalopathy when accompanied by excessive fluid ingestion. The mechanism involves inappropriate secretion of antidiuretic hormone.
Comparable studies
Other narrative reviews on MDMA, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Human Pharmacology of MDMA | 2004 | Review | |
| Human psychopharmacology of Ecstasy (MDMA): a review of 15 years of empirical research | 2001 | Review | |
| 3,4‐Methylenedioxymethamphetamine (MDMA, “Ecstasy”): pharmacology and toxicology in animals and humans | 1994 | Review | |
| (±)3,4-Methylenedioxymethamphetamine (‘Ecstasy’)-Induced Serotonin Neurotoxicity: Studies in Animals | 2000 | Review | |
| Amphetamine toxicities | 2010 | Review |
Citations in the library
Cited by 27
- Human Pharmacology of MDMA Therapeutic Drug Monitoring March 19, 2004
- Designer drugs: mechanism of action and adverse effects Archives of Toxicology April 1, 2020
- Safety pharmacology of acute MDMA administration in healthy subjects Journal of Psychopharmacology February 21, 2017
- Sex Differences in the Effects of MDMA (Ecstasy) on Plasma Copeptin in Healthy Subjects The Journal of Clinical Endocrinology & Metabolism June 30, 2011
- Effects of MDMA on body temperature in humans Temperature October 31, 2014
and 22 more in the library
Cites 4
- Recreational MDMA use in Sydney: a profile of ‘Ecstasy’ users and their experiences with the drug British Journal of Addiction August 1, 1992
- Pathology of deaths associated with "ecstasy" and "eve" misuse. Journal of Clinical Pathology February 1, 1996
- Cerebral oedema after ingestion of MDMA (“ecstasy”) and unrestricted intake of water BMJ May 25, 1996
- Toxicity and deaths from 3,4-methylenedioxymethamphetamine ("ecstasy"). The Lancet August 15, 1992