The Ghosts of Ayahuasca: Conceptual Limits and Spectral Residues
Jacob W. Glazier, Sean O’donnell
Anthropology of Consciousness September 25, 2025 DOI: 10.1111/anoc.70013 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Theoretical or philosophical paper Peer reviewed |
|---|---|
| Topics | Ayahuasca |
| Key points | Argues that ayahuasca's spectral residues disrupt materialist understandings of reality, challenging models and inviting broader reflections on consciousness, interconnection, death, and metaphysical limits. |
Abstract
ABSTRACT This essay explores the conceptual and philosophical complexities surrounding ayahuasca use, focusing on its ability to reveal ghosts through the lens of hauntology. Ayahuasca, a psychoactive brew traditionally used in shamanic rituals, is known to evoke profound experiences involving spirits, mystical entities, and transformative states of consciousness. The brew's active compound, dimethyltryptamine (DMT), is notable for its dual nature as both an endogenous neurotransmitter and an exogenous psychedelic. This duality unsettles the boundary between what is natural to the human body and what is external, inviting a reconsideration of anthropocentric and biomedical assumptions. Furthermore, encounters with discarnate beings during ayahuasca journeys blur the lines between corporeality and incorporeality, suggesting that these entities—while phenomenologically real—defy categorization within traditional ontological frameworks. Ultimately, we argue that ayahuasca's spectral residues disrupt materialist understandings of reality, leaving traces that haunt these models and invite broader reflections on consciousness, interconnection, death, and metaphysical limits. By listening to these ghosts, both as conceptual provocations and as subjective experiences, we can challenge and expand our understanding of reality while embracing the transformative and scary possibilities ayahuasca presents.
Comparable studies
Other theoretical and historical papers on ayahuasca, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| The globalization of ayahuasca: Harm reduction or benefit maximization? | 2006 | Theoretical or philosophical paper | |
| Ayahuasca Shamanism in the Amazon and Beyond | 2014 | Theoretical or philosophical paper | |
| The Antipodes of the Mind: Charting the Phenomenology of the Ayahuasca Experience | 2003 | Theoretical or philosophical paper | |
| Towards psychedelic apprenticeship: Developing a gentle touch for the mediation and validation of psychedelic-induced insights and revelations. | 2022 | Theoretical or philosophical paper | |
| Ayahuasca healing beyond the Amazon: the globalization of a traditional indigenous entheogenic practice | 2008 | Theoretical or philosophical paper |
Citations in the library
Cites 30
- The Hallucinogen N,N -Dimethyltryptamine (DMT) Is an Endogenous Sigma-1 Receptor Regulator Science February 13, 2009
- Monoamine oxidase inhibitors in South American hallucinogenic plants: Tryptamine and β-carboline constituents of Ayahuasca Journal of Ethnopharmacology April 1, 1984
- Clinical investigations of the therapeutic potential of ayahuasca: rationale and regulatory challenges. Pharmacology & Therapeutics May 1, 2004
- Survey of subjective "God encounter experiences": Comparisons among naturally occurring experiences and those occasioned by the classic psychedelics psilocybin, LSD, ayahuasca, or DMT PLoS One April 23, 2019
- DMT Models the Near-Death Experience Frontiers in Psychology August 15, 2018
and 25 more in the library