Psychedelic trip sitting, dosages and intensities: Supplementing clinical studies with anecdotal reports
Liam Engel, Sascha Thal, Stephen Bright, Mitchell Low
Journal of Psychedelic Studies July 17, 2024 DOI: 10.1556/2054.2024.00377 (opens in new tab)
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Study at a glance
AI-extracted from the abstract| Characteristics | Qualitative study with Delphi-style expert panel review Peer reviewed |
|---|---|
| Sample size | 660 |
| Population | Posts from online psychedelic forums (The Shroomery and DMT Nexus) on trip sitting |
| Topics | Mescaline Psilocybin |
| Keywords | Delphi method Hallucinogen Dose |
| Citations | 4 |
| Key findings | Greater psychedelic purity and dosage intensity correlated with a perceived need for care, and 5-MeO-DMT was strongly associated with a perceived need for care. |
Abstract
Abstract Background and aims Online communities provide insights into psychedelic consumption, assisting in identification of trends, informing both harm reduction provisions and clinical research. This study extracts forum data on psychedelic substances, dosages, and administration routes, categorising and analysing self-reported consumption to inform care services and guide clinical work with psychedelics.
Methods: Posts ( n = 660) from online psychedelic forums (The Shroomery and DMT Nexus) on 'trip sitting' were analysed. Using a Delphi-style expert panel review facilitated by LE, we created drug weight and intensity charts (threshold, light, common, strong and heavy dosages) for psychedelics discussed in these posts. The psychedelic substance, dosage intensity and route of administration [ROA] (smoked/vaporised, oral, injected, insufflated and undisclosed) frequencies and exploring correlations with perceived need for assistance from a psychedelic carer were mapped and correlated with perceived need for psychedelic care.
Results: Psychedelics appearing in our data were 5-MeO-DMT, ayahuasca, changa, LSA, LSD and psilocybin. There was greater commonality between clinical studies and 'common' doses determined through the Delphi method, for more extensively researched substances like LSD and psilocybin. Many posts indicated opinions that psychedelic care was unnecessary or optional for consumers, particularly for LSD and LSA. 5-MeO-DMT was strongly associated with a perceived need for care. A correlation was identified between greater psychedelic purity, dosage intensity, and a perceived need for care. Oral administration, the most common ROA, showed lower dosage intensity.
Conclusion: More research is needed to understand factors influencing psychedelic care practices. Educational information, emphasizing risk management strategies, should be provided to psychedelic consumers, emphasising psychedelic products and administration methods more likely to be dosed at a strong or heavy intensity.
Comparable studies
Other qualitative studies on mescaline, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Peyote as Earth Medicine: Examining How Symbolic Meanings Shape Experiences With Psychedelics People who use peyote in religious ceremonies | 2023 | Photo-ethnography | |
| The Use of Peyote as Treatment for Alcoholism within the NAC Community: Reflections on a Study | 2011 | Interview | |
| Hitting the Reset Button: Ceremonial Use of Peyote and Experiences of Personal Change People who attended peyote ceremonies in rural Northcentral Alabama | 2024 | Photo-ethnography | |
| The San Pedro Cactus (Equinopsis pachanoi): Ancestral and Modern Therapeutic Uses in Peru Curanderos in the Túcume district of northern Peru | 2025 | Qualitative study | |
| The Trouble With Psychedelic Cacti: Conflicting Meanings of San Pedro and Peyote | 2025 | Autoethnography |
Citations in the library
Cited by 3
- A UHPLC-(ESI)MS/MS method for the determination of the psychedelic secondary metabolite mescaline in San Pedro (Trichocereus spp.) and its applicability for screening mescaline in other cacti varieties. Forensic Chemistry March 25, 2025
- The Trouble With Psychedelic Cacti: Conflicting Meanings of San Pedro and Peyote Contemporary Drug Problems February 10, 2025
- Sombras, introspección y rescate interior: un estudio de caso sobre el uso de psilocibina en contexto doméstico JOURNAL OF NEUROSCIENCE AND PUBLIC HEALTH August 6, 2024
Cites 57
- Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial Journal of Psychopharmacology November 30, 2016
- Rapid and sustained symptom reduction following psilocybin treatment for anxiety and depression in patients with life-threatening cancer: a randomized controlled trial Journal of Psychopharmacology November 30, 2016
- Psilocybin with psychological support for treatment-resistant depression: an open-label feasibility study. The Lancet Psychiatry May 17, 2016
- Trial of Psilocybin versus Escitalopram for Depression New England Journal of Medicine April 14, 2021
- Effects of Psilocybin-Assisted Therapy on Major Depressive Disorder JAMA Psychiatry November 4, 2020
and 52 more in the library