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Exploring the effect of microdosing psychedelics on creativity in an open-label natural setting

Luisa Prochazkova, Dominique P. Lippelt, Lorenza S. Colzato, Martin Kuchař, Zsuzsika Sjoerds, Bernhard Hommel

Psychopharmacology October 24, 2018 DOI: 10.1007/s00213-018-5049-7 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Preliminary study Placebo-controlled Open-label Peer reviewed
Population Adults microdosing in natural settings
Intervention microdosing psychedelics
Topics Microdosing
Keywords Creativity Cognition Divergent thinking Flexibility engineering Cognitive flexibility Cognitive psychology Task project management Microdose Pharmacology
Citations 181
Key points Microdosing psychedelics may enhance cognitive performance by optimizing the balance between cognitive persistence and flexibility.

Abstract

While this study provides quantitative support for the cognitive-enhancing properties of microdosing psychedelics, future research has to confirm these preliminary findings in more rigorous placebo-controlled study designs. Based on these preliminary results, we speculate that psychedelics might affect cognitive metacontrol policies by optimizing the balance between cognitive persistence and flexibility. We hope this study will motivate future microdosing studies with more controlled designs to test this hypothesis.