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Long-term Amelioration of OCD Symptoms in a Patient with Chronic Consumption of Psilocybin-containing Mushrooms

Agustín Lugo-Radillo, Jorge Luis Cortés-lópez

Journal of Psychoactive Drugs November 22, 2020 DOI: 10.1080/02791072.2020.1849879 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Case study Case report Peer reviewed
Sample size 1
Population Male adult with OCD
Intervention Psilocybin-containing mushrooms
Topics Psilocybin
Keywords Hallucinogen Obsessive compulsive Psychoactive substance
Citations 34
Key findings A male adult with OCD showed a clinically meaningful reduction in OCD symptoms after consuming psilocybin-containing mushrooms.

Abstract

Obsessive Compulsive Disorder (OCD) is a chronic neuropsychiatric condition, characterized by obsessions and compulsions, which is usually disabling for the suffering individual. The first-line treatment is not effective in all patients. There is evidence showing the effectiveness of psilocybin and psilocybin-containing mushrooms in the treatment of OCD symptoms. We present the case of a male adult with OCD who showed a clinically meaningful reduction of his OCD symptomatology after the consumption of psilocybin-containing mushrooms. Future research will determine if psilocybin and other psychoactive compounds of psilocybin-containing mushrooms are effective and safe for the treatment of OCD.

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