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Serotonergic Psychedelics in Neural Plasticity

Kacper Łukasiewicz, Jacob J. Baker, Yi Zuo, Ju Lu

Frontiers in Molecular Neuroscience October 12, 2021 DOI: 10.3389/fnmol.2021.748359 (opens in new tab)

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AI-extracted from the abstract
Characteristics Review Peer reviewed
Topics Neuroplasticity Serotonin
Keywords Focus optics
Citations 32
Key findings Classical serotonergic psychedelics induce neural plasticity by promoting neurite growth and synapse formation, which may contribute to their therapeutic potential.

Abstract

Psychedelics, compounds that can induce dramatic changes in conscious experience, have been used by humans for centuries. Recent studies have shown that certain psychedelics can induce neural plasticity by promoting neurite growth and synapse formation. In this review, we focus on the role of classical serotonergic psychedelics in neural plasticity and discuss its implication for their therapeutic potentials.

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