Loss of Consciousness and Visual Hallucinations Related to 5-MeO-DALT Intake, a Case Report Confirmed by Toxicological Analyses.
Laurène Dufayet, Jérôme Langrand, Jean-Claude Alvarez, Amine Islam Larabi
Journal of Analytical Toxicology August 13, 2022 DOI: 10.1093/jat/bkac021 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Case study Case report Peer reviewed |
|---|---|
| Sample size | 1 |
| Population | A 46-year-old man |
| Intervention | 5-MeO-DALT |
| Dose | three 5-MeO-DALT tablets (32.5 mg per tablet, 11% purity) |
| Topics | 5-MeO-DMT |
| Citations | 3 |
| Key findings | Ingestion of 5-MeO-DALT tablets caused brief loss of consciousness and visual hallucinations, and the drug was quantified in the tablets and patient's plasma. |
Abstract
5-MeO-DALT or 5-methoxy-N,N-diallyltryptamine is a derivative of tryptamines, consumed for its hallucinogenic and entheogenic effects. We report the case of a 46-year-old-man, presenting with a brief loss of consciousness and visual hallucinations, after the consumption of three 5-MeO-DALT tablets bought online. Liquid chromatography coupled to tandem mass spectrometry method was performed, and 5-MeO-DALT was quantified in both the tablets (32.5 mg per tablet, 11% of purity) and the patient's plasma (7 ng/mL-8 h between the consumption and the blood sample). 5-MeO-DALT poisonings are rarely described. Given the broad availability of these products, it is important that emergency department physicians and clinical toxicologists do not overlook the possibility of the ingestion of recreational tryptamines, especially since they are not detected by most routine toxicological screening.
Comparable studies
Other case reports and case series on 5-MeO-DMT, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| A fatal intoxication following the ingestion of 5-methoxy-N,N-dimethyltryptamine in an ayahuasca preparation. 25-year-old white male | 2005 | Case study | n = 1 |
| Combined intoxication with methylone and 5-MeO-MIPT 27-year-old male patient | 2006 | Case report | n = 1 |
| Sudden death associated with intravenous injection of toad extract. A 24-year-old male | 2009 | Case study | n = 1 |
| 5-Meo-DALT-induced Cyclic Myoclonus (P3.013) A 29-year-old man with history of heroin and marijuana abuse | 2015 | Case report | n = 1 |
| A case report SPECT study and theoretical rationale for the sequential administration of ibogaine and 5-MeO-DMT in the treatment of alcohol use disorder. 31-year-old male military veteran with moderate alcohol use disorder | 2018 | Case study | n = 1 |
Citations in the library
Cited by 2
- Serotonin 1A Receptors Modulate Serotonin 2A Receptor-Mediated Behavioral Effects of 5-Methoxy-N,N-dimethyltryptamine Analogs in Mice. ACS Chemical Neuroscience December 18, 2024
- Toxicokinetics and analytical toxicology of four N, N-dimethyltryptamine derivatives studied in human in vitro systems and in vivo by means of zebrafish embryos. Archives of Toxicology September 21, 2026
Cites 6
- The hallucinogenic world of tryptamines: an updated review. Archives of Toxicology August 1, 2015
- Recreational Use, Analysis and Toxicity of Tryptamines Current Neuropharmacology December 10, 2014
- The recreational tryptamine 5-MeO-DALT (N,N-diallyl-5-methoxytryptamine): a brief review. Progress in Neuro-Psychopharmacology and Biological Psychiatry December 3, 2012
- Delirium Due to Intoxication from the Novel Synthetic Tryptamine 5‐MeO‐DALT Journal of Forensic Sciences December 13, 2013
- Receptor binding profiles and behavioral pharmacology of ring-substituted N,N-diallyltryptamine analogs. Neuropharmacology November 1, 2018
and 1 more in the library