Effect of Integrated Yoga as an add-on therapy in adults with clinical depression - A randomized controlled trial.
Anu James Vibin, Niharika Niharika, Varun Valliappan, Pasang Lamo, Niranjan Parajuli, Mansingh Jat, Sudha Lama, Aman Agarwal, Rajesh Sagar, Gautam Sharma
International Journal of Social Psychiatry June 1, 2024 DOI: 10.1177/00207640231223431 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Randomized controlled trial Peer reviewed |
|---|---|
| Population | Adults aged 18 to 64 with clinical depression at a tertiary care hospital in India |
| Intervention | Integrated Yoga Module |
| Duration | 8-week intervention |
| Topics | Meditation Depression |
| Keywords | Yoga Clinical depression Resilience Self-compassion |
| Citations | 2 |
| Key findings | The Integrated Yoga Module added to standard care with yogic education significantly reduced depression symptoms and improved resilience and physical health compared to standard care with yogic education alone. |
Abstract
Depression is a leading cause of disability and the conventional management has several limitations. Recent studies demonstrated the benefits of yoga in psychological disorders. To evaluate the efficacy of the Integrated Yoga Module (IYM) to standard care with added yogic education on lifestyle modification (YELM) in patients with clinical depression. A PROBE trial was conducted at a single tertiary care hospital in India. Adults aged 18 to 64 with clinical depression were randomized to either an IYM or an active control group using a computer-generated mixed block randomization sequence. Both groups received YELM in addition to standard care and the intervention group practiced IYM, for 8 weeks. The primary outcome was the reduction in depression symptoms assessed using the Beck Depression Inventory (BDI-II), and secondary outcomes involved self-compassion, brief resilience, positive and negative experiences, and quality of life, evaluated at 8 weeks. The mean ± SD age of participants was 32.2 ± 10.0 and 54.3% were females. The IYM group showed statistically significant improvements in BDI-II scores β = -6.7 (95% CI [-10.8, -2.5]; p = .001), resilience β = 0.4 (95% CI [0.02, 0.80]; p = .037), physical health domain of WHOQOL - BREF β = 10.1 (95% CI [0.7, 19.5]; p = .035) and negative emotions (SPANE-N) β = 2.8 (95% CI [0.1, 5.4]; p = .037). However, no significant differences were found in SCS-SF β = -0.3 (95% CI [-0.7, 0.0]; p = .053). IYM as an adjunct is superior to conventional medical management in reducing symptoms and improving positive psychological resources in clinical depression.
Comparable studies
Other randomized controlled trials on depression, most cited first.
Citations in the library
Cites 5
- Effects of Mindfulness Yoga vs Stretching and Resistance Training Exercises on Anxiety and Depression for People With Parkinson Disease: A Randomized Clinical Trial. JAMA Neurology July 1, 2019
- A Breathing-based Meditation Intervention for Patients with Major Depressive Disorder Following Inadequate Response to Antidepressants: A Randomized Pilot Study The Journal of Clinical Psychiatry 2017
- Meditation and Yoga can Modulate Brain Mechanisms that affect Behavior and Anxiety-A Modern Scientific Perspective. Anc Sci April 1, 2015
- Potential self-regulatory mechanisms of yoga for psychological health. Frontiers in Human Neuroscience 2014
- Increased dopamine tone during meditation-induced change of consciousness. Brain research. Cognitive brain research April 2002